SNP Detail For rs12580533
1.Mapping Information
Human SNP ID rs12580533
Human chromosome chr12
Human SNP position 129162056
Pig chromosome chr14
Pig SNP position 27492032
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region12q24.33
Chromosome idchr12
Chromosome position129162056
Reported geneNR
Mapped geneTMEM132D
Upstream gene id
Downstream gene id
SNP gene ids121256
Upstream gene distance
Downstream gene distance
SNP risk allelers12580533-C
SNPsrs12580533
Merged0
SNP id current12580533
Contextintron_variant
Intergenic0
Allele frequency0.014010396137832
P value0.000008
Pvalue mlog5.09691001300805
P value text(IGP33)
Or beta0.8247
%95 Ci[0.46-1.19] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848