Human SNP ID | rs12579720 |
---|---|
Human chromosome | chr12 |
Human SNP position | 20020830 |
Pig chromosome | chr5 |
Pig SNP position | 56330638 |
PubMed ID | 26390057 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26390057 |
Study | Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. |
Disease/Trait | Diastolic blood pressure |
Initial sample | 31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals |
Replication sample | 87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals, 16,328 South Asian ancestry individuals |
Region | 12p12.2 |
Chromosome id | chr12 |
Chromosome position | 20020830 |
Reported gene | PDE3A |
Mapped gene | LOC100506393 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 100506393 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs12579720-C |
SNPs | rs12579720 |
Merged | 0 |
SNP id current | 12579720 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.316614178 |
P value | 0.0000000000000002 |
Pvalue mlog | 15.698970004336 |
P value text | |
Or beta | 0.3193904 |
%95 Ci | [0.24-0.4] mmHg decrease |
Platform | Affymetrix, Illumina, Perlegen [~ 2100000] (imputed) |
CNV | N |
Mapped trait | diastolic blood pressure |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006336 |
Study accession | GCST003273 |