SNP Detail For rs12542166
1.Mapping Information
Human SNP ID rs12542166
Human chromosome chr8
Human SNP position 121970599
Pig chromosome chr4
Pig SNP position 18174441
2.Annotation Information
PubMed ID24578207
JournalStroke
Linkwww.ncbi.nlm.nih.gov/pubmed/24578207
StudyGenome-wide genotyping demonstrates a polygenic risk score associated with white matter hyperintensity volume in CADASIL.
Disease/TraitWhite matter hyperintensity volume in cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy
Initial sample466 European ancestry individuals
Replication sampleNA
Region8q24.13
Chromosome idchr8
Chromosome position121970599
Reported geneNR
Mapped geneLOC105375732 - LOC105375733
Upstream gene id105375732
Downstream gene id105375733
SNP gene ids
Upstream gene distance286006
Downstream gene distance368137
SNP risk allelers12542166-C
SNPsrs12542166
Merged0
SNP id current12542166
Contextintron_variant
Intergenic1
Allele frequencyNR
P value0.000006
Pvalue mlog5.22184874961635
P value text
Or beta0.1056
%95 Ci[NR] unit increase
PlatformAffymetrix [583499]
CNVN
Mapped traitCADASIL, white matter hyperintensity measurement
Mapped trait URIhttp://www.orpha.net/ORDO/Orphanet_136, http://www.ebi.ac.uk/efo/EFO_0005665
Study accessionGCST002377