Human SNP ID | rs12542166 |
---|---|
Human chromosome | chr8 |
Human SNP position | 121970599 |
Pig chromosome | chr4 |
Pig SNP position | 18174441 |
PubMed ID | 24578207 |
---|---|
Journal | Stroke |
Link | www.ncbi.nlm.nih.gov/pubmed/24578207 |
Study | Genome-wide genotyping demonstrates a polygenic risk score associated with white matter hyperintensity volume in CADASIL. |
Disease/Trait | White matter hyperintensity volume in cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy |
Initial sample | 466 European ancestry individuals |
Replication sample | NA |
Region | 8q24.13 |
Chromosome id | chr8 |
Chromosome position | 121970599 |
Reported gene | NR |
Mapped gene | LOC105375732 - LOC105375733 |
Upstream gene id | 105375732 |
Downstream gene id | 105375733 |
SNP gene ids | |
Upstream gene distance | 286006 |
Downstream gene distance | 368137 |
SNP risk allele | rs12542166-C |
SNPs | rs12542166 |
Merged | 0 |
SNP id current | 12542166 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.000006 |
Pvalue mlog | 5.22184874961635 |
P value text | |
Or beta | 0.1056 |
%95 Ci | [NR] unit increase |
Platform | Affymetrix [583499] |
CNV | N |
Mapped trait | CADASIL, white matter hyperintensity measurement |
Mapped trait URI | http://www.orpha.net/ORDO/Orphanet_136, http://www.ebi.ac.uk/efo/EFO_0005665 |
Study accession | GCST002377 |