SNP Detail For rs12537
1.Mapping Information
Human SNP ID rs12537
Human chromosome chr22
Human SNP position 30027471
Pig chromosome chr14
Pig SNP position 50060943
2.Annotation Information
PubMed ID22197929
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22197929
StudyA genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy.
Disease/TraitIgA nephropathy
Initial sample1,434 Han Chinese ancestry cases, 4,270 Han Chinese ancestry controls
Replication sample2,703 Han Chinese ancestry cases, 3,464 Han Chinese ancestry controls
Region22q12.2
Chromosome idchr22
Chromosome position30027471
Reported geneMTMR3
Mapped geneMTMR3, HORMAD2-AS1
Upstream gene id
Downstream gene id
SNP gene ids8897, 101929664
Upstream gene distance
Downstream gene distance
SNP risk allelers12537-C
SNPsrs12537
Merged0
SNP id current12537
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.81
P value0.00000000001
Pvalue mlog11
P value text
Or beta1.28
%95 Ci[1.19-1.39]
PlatformIllumina [444882]
CNVN
Mapped traitIGA glomerulonephritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004194
Study accessionGCST001364
PubMed ID26028593
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/26028593
StudyIdentification of new susceptibility loci for IgA nephropathy in Han Chinese.
Disease/TraitIgA nephropathy
Initial sample1,434 Han Chinese ancestry cases, 10,661 Han Chinese ancestry controls
Replication sample6,879 Han Chinese ancestry cases, 9,019 Han Chinese ancestry controls
Region22q12.2
Chromosome idchr22
Chromosome position30027471
Reported geneHORMAD2
Mapped geneMTMR3, HORMAD2-AS1
Upstream gene id
Downstream gene id
SNP gene ids8897, 101929664
Upstream gene distance
Downstream gene distance
SNP risk allelers12537-C
SNPsrs12537
Merged0
SNP id current12537
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.817
P value0.000000003
Pvalue mlog8.52287874528033
P value text
Or beta1.407
%95 Ci[1.258-1.573]
PlatformIllumina [3792949] (imputed)
CNVN
Mapped traitIGA glomerulonephritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004194
Study accessionGCST002943