SNP Detail For rs12534221
1.Mapping Information
Human SNP ID rs12534221
Human chromosome chr7
Human SNP position 131603231
Pig chromosome chr18
Pig SNP position 18495330
2.Annotation Information
PubMed ID20932310
JournalBMC Neurol
Linkwww.ncbi.nlm.nih.gov/pubmed/20932310
StudyGenome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study.
Disease/TraitCerebrospinal AB1-42 levels
Initial sample172 European ancestry Alzheimer__s disease cases, 109 European ancestry mild cognitive impairment cases, 109 European ancestry controls
Replication sampleNA
Region7q32.3
Chromosome idchr7
Chromosome position131603231
Reported geneintergenic
Mapped genePODXL - EEF1B2P6
Upstream gene id5420
Downstream gene id647030
SNP gene ids
Upstream gene distance46614
Downstream gene distance58669
SNP risk allelers12534221-A
SNPsrs12534221
Merged0
SNP id current12534221
Contextregulatory_region_variant
Intergenic1
Allele frequencyNR
P value0.0000009
Pvalue mlog6.04575749056067
P value text(Controls)
Or beta
%95 Ci
PlatformIllumina [498205]
CNVN
Mapped traitbeta-amyloid 1-42 measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004670
Study accessionGCST000827