Human SNP ID | rs1250540 |
---|---|
Human chromosome | chr10 |
Human SNP position | 79276250 |
Pig chromosome | chr14 |
Pig SNP position | 88269367 |
PubMed ID | 19525953 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19525953 |
Study | Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. |
Disease/Trait | Multiple sclerosis |
Initial sample | 2,624 European ancestry cases, 7,220 European ancestry controls |
Replication sample | 2,215 European ancestry cases, 2,116 European ancestry controls |
Region | 10q22.3 |
Chromosome id | chr10 |
Chromosome position | 79276250 |
Reported gene | ZMIZ1 |
Mapped gene | ZMIZ1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 57178 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1250540-G |
SNPs | rs1250540 |
Merged | 0 |
SNP id current | 1250540 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.35 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | |
Or beta | 1.12 |
%95 Ci | [1.02-1.22] |
Platform | Affymetrix, Illumina [~ 2560000] (imputed) |
CNV | N |
Mapped trait | multiple sclerosis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003885 |
Study accession | GCST000424 |