SNP Detail For rs1250540
1.Mapping Information
Human SNP ID rs1250540
Human chromosome chr10
Human SNP position 79276250
Pig chromosome chr14
Pig SNP position 88269367
2.Annotation Information
PubMed ID19525953
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19525953
StudyMeta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
Disease/TraitMultiple sclerosis
Initial sample2,624 European ancestry cases, 7,220 European ancestry controls
Replication sample2,215 European ancestry cases, 2,116 European ancestry controls
Region10q22.3
Chromosome idchr10
Chromosome position79276250
Reported geneZMIZ1
Mapped geneZMIZ1
Upstream gene id
Downstream gene id
SNP gene ids57178
Upstream gene distance
Downstream gene distance
SNP risk allelers1250540-G
SNPsrs1250540
Merged0
SNP id current1250540
Contextintron_variant
Intergenic0
Allele frequency0.35
P value0.000002
Pvalue mlog5.69897000433601
P value text
Or beta1.12
%95 Ci[1.02-1.22]
PlatformAffymetrix, Illumina [~ 2560000] (imputed)
CNVN
Mapped traitmultiple sclerosis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003885
Study accessionGCST000424