Human SNP ID | rs12472911 |
---|---|
Human chromosome | chr2 |
Human SNP position | 141470940 |
Pig chromosome | chr15 |
Pig SNP position | 11227325 |
PubMed ID | 21102462 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21102462 |
Study | Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. |
Disease/Trait | Menarche (age at onset) |
Initial sample | 86,142 European ancestry female individuals, 557 Old Order Amish female individuals, 1,103 Erasmus Rucphen female individuals |
Replication sample | Up to 12,813 European ancestry female individuals, 910 Val Borbera female individuals, 348 Orcadian female individuals, 338 Friuli Venezia Giulia female individuals, 322 Carlantino female individuals |
Region | 2q22.1 |
Chromosome id | chr2 |
Chromosome position | 141470940 |
Reported gene | LRP1B |
Mapped gene | LRP1B, LOC105373649 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 53353, 105373649 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs12472911-C |
SNPs | rs12472911 |
Merged | 0 |
SNP id current | 12472911 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.2 |
P value | 0.0000002 |
Pvalue mlog | 6.69897000433601 |
P value text | |
Or beta | 2.5 |
%95 Ci | [1.52-3.48] week increase |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | age at menarche |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004703 |
Study accession | GCST000880 |
PubMed ID | 25231870 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25231870 |
Study | Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. |
Disease/Trait | Menarche (age at onset) |
Initial sample | Up to 182,413 European ancestry females |
Replication sample | NA |
Region | 2q22.1 |
Chromosome id | chr2 |
Chromosome position | 141470940 |
Reported gene | LRP1B |
Mapped gene | LRP1B, LOC105373649 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 53353, 105373649 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs12472911-C |
SNPs | rs12472911 |
Merged | 0 |
SNP id current | 12472911 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.2 |
P value | 0.0000000007 |
Pvalue mlog | 9.15490195998574 |
P value text | |
Or beta | 0.04 |
%95 Ci | [0.028-0.052] unit increase |
Platform | Affymetrix, Illumina [2441815] (imputed) |
CNV | N |
Mapped trait | age at menarche |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004703 |
Study accession | GCST002541 |