Human SNP ID | rs12465515 |
---|---|
Human chromosome | chr2 |
Human SNP position | 217029680 |
Pig chromosome | chr15 |
Pig SNP position | 131974291 |
PubMed ID | 26301497 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26301497 |
Study | Genetic association analyses highlight biological pathways underlying mitral valve prolapse. |
Disease/Trait | Mitral valve prolapse |
Initial sample | 1,442 European ancestry cases, 2,439 European ancestry controls |
Replication sample | 1,422 European ancestry cases, 6,779 European ancestry controls |
Region | 2q35 |
Chromosome id | chr2 |
Chromosome position | 217029680 |
Reported gene | IGFBP5, TNS1, TNP1, IGFBP2, DIRC3 |
Mapped gene | LOC101928278 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 101928278 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs12465515-C |
SNPs | rs12465515 |
Merged | |
SNP id current | 12465515 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.34 |
P value | 0.00000000003 |
Pvalue mlog | 10.5228787452803 |
P value text | |
Or beta | 1.25 |
%95 Ci | [1.18-1.33] |
Platform | Affymetrix, Illumina [~ 4800000] (imputed) |
CNV | N |
Mapped trait | Mitral valve prolapse |
Mapped trait URI | http://purl.obolibrary.org/obo/HP_0001634 |
Study accession | GCST003094 |