SNP Detail For rs12465515
1.Mapping Information
Human SNP ID rs12465515
Human chromosome chr2
Human SNP position 217029680
Pig chromosome chr15
Pig SNP position 131974291
2.Annotation Information
PubMed ID26301497
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26301497
StudyGenetic association analyses highlight biological pathways underlying mitral valve prolapse.
Disease/TraitMitral valve prolapse
Initial sample1,442 European ancestry cases, 2,439 European ancestry controls
Replication sample1,422 European ancestry cases, 6,779 European ancestry controls
Region2q35
Chromosome idchr2
Chromosome position217029680
Reported geneIGFBP5, TNS1, TNP1, IGFBP2, DIRC3
Mapped geneLOC101928278
Upstream gene id
Downstream gene id
SNP gene ids101928278
Upstream gene distance
Downstream gene distance
SNP risk allelers12465515-C
SNPsrs12465515
Merged
SNP id current12465515
Contextintergenic_variant
Intergenic0
Allele frequency0.34
P value0.00000000003
Pvalue mlog10.5228787452803
P value text
Or beta1.25
%95 Ci[1.18-1.33]
PlatformAffymetrix, Illumina [~ 4800000] (imputed)
CNVN
Mapped traitMitral valve prolapse
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0001634
Study accessionGCST003094