SNP Detail For rs1245582
1.Mapping Information
Human SNP ID rs1245582
Human chromosome chr10
Human SNP position 72018509
Pig chromosome chr14
Pig SNP position 80784887
2.Annotation Information
PubMed ID24216480
JournalJ Clin Invest
Linkwww.ncbi.nlm.nih.gov/pubmed/24216480
StudyLumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant.
Disease/TraitDisc degeneration (lumbar)
Initial sample366 Japanese ancestry cases, 3,331 Japanese ancestry controls
Replication sample1,628 East Asian ancestry cases, 17,469 East Asian ancestry controls, 399 European ancestry cases, 5,035 European ancestry control
Region10q22.1
Chromosome idchr10
Chromosome position72018509
Reported geneCHST3
Mapped geneCHST3 - SPOCK2
Upstream gene id9469
Downstream gene id9806
SNP gene ids
Upstream gene distance4945
Downstream gene distance40525
SNP risk allelers1245582-?
SNPsrs1245582
Merged0
SNP id current1245582
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.44
P value0.000001
Pvalue mlog6
P value text(East Asians)
Or beta
%95 Ci
PlatformIllumina [464775]
CNVN
Mapped traitlumbar disc degeneration
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004994
Study accessionGCST002225
PubMed ID24216480
JournalJ Clin Invest
Linkwww.ncbi.nlm.nih.gov/pubmed/24216480
StudyLumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant.
Disease/TraitDisc degeneration (lumbar)
Initial sample366 Japanese ancestry cases, 3,331 Japanese ancestry controls
Replication sample1,628 East Asian ancestry cases, 17,469 East Asian ancestry controls, 399 European ancestry cases, 5,035 European ancestry control
Region10q22.1
Chromosome idchr10
Chromosome position72018509
Reported geneCHST3
Mapped geneCHST3 - SPOCK2
Upstream gene id9469
Downstream gene id9806
SNP gene ids
Upstream gene distance4945
Downstream gene distance40525
SNP risk allelers1245582-?
SNPsrs1245582
Merged0
SNP id current1245582
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.44
P value0.00000004
Pvalue mlog7.39794000867203
P value text
Or beta1.2
%95 Ci[1.13-1.29]
PlatformIllumina [464775]
CNVN
Mapped traitlumbar disc degeneration
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004994
Study accessionGCST002225