SNP Detail For rs12451840
1.Mapping Information
Human SNP ID rs12451840
Human chromosome chr17
Human SNP position 73811574
Pig chromosome chr12
Pig SNP position 7269773
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region17q25.1
Chromosome idchr17
Chromosome position73811574
Reported geneNR
Mapped geneLINC00469
Upstream gene id
Downstream gene id
SNP gene ids283982
Upstream gene distance
Downstream gene distance
SNP risk allelers12451840-C
SNPsrs12451840
Merged0
SNP id current12451840
Contextintron_variant
Intergenic0
Allele frequency0.0417941590759076
P value0.000003
Pvalue mlog5.52287874528033
P value text(IGP23)
Or beta0.7321
%95 Ci[0.42-1.04] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848