SNP Detail For rs12446554
1.Mapping Information
Human SNP ID rs12446554
Human chromosome chr16
Human SNP position 19923751
Pig chromosome chr3
Pig SNP position 26611010
2.Annotation Information
PubMed ID23563607
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23563607
StudyGenome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Disease/TraitObesity
Initial sample93,015 European ancestry overweight individuals, 32,858 European ancestry class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls
Replication sample65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls
Region16p12.3
Chromosome idchr16
Chromosome position19923751
Reported geneGPRC5B
Mapped geneLOC105371116
Upstream gene id
Downstream gene id
SNP gene ids105371116
Upstream gene distance
Downstream gene distance
SNP risk allelers12446554-G
SNPsrs12446554
Merged0
SNP id current12446554
Contextintergenic_variant
Intergenic0
Allele frequency0.86
P value0.000000000004
Pvalue mlog11.397940008672
P value text(Overweight)
Or beta1.07
%95 Ci[NR]
PlatformAffymetrix, Illumina [~ 2800000] (imputed)
CNVN
Mapped traitobesity
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001073
Study accessionGCST001953