SNP Detail For rs12436689
1.Mapping Information
Human SNP ID rs12436689
Human chromosome chr14
Human SNP position 85187675
Pig chromosome chr7
Pig SNP position 113945221
2.Annotation Information
PubMed ID22424883
JournalJ Allergy Clin Immunol
Linkwww.ncbi.nlm.nih.gov/pubmed/22424883
StudyGenome-wide association study of lung function decline in adults with and without asthma.
Disease/TraitPulmonary function decline
Initial sample1,441 European ancestry asthma cases, 2,677 European ancestry controls
Replication sample1,160 European ancestry asthma cases, 10,858 European ancestry controls
Region14q31.3
Chromosome idchr14
Chromosome position85187675
Reported geneFLRT2
Mapped geneLOC105370604
Upstream gene id
Downstream gene id
SNP gene ids105370604
Upstream gene distance
Downstream gene distance
SNP risk allelers12436689-?
SNPsrs12436689
Merged0
SNP id current12436689
Contextintergenic_variant
Intergenic0
Allele frequencyNR
P value0.000007
Pvalue mlog5.15490195998574
P value text(FEV1 decline in asthmatics)
Or beta0.2117
%95 Ci[0.12-0.30] unit decrease
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitforced expiratory volume
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314
Study accessionGCST001444