SNP Detail For rs12435940
1.Mapping Information
Human SNP ID rs12435940
Human chromosome chr14
Human SNP position 25552779
Pig chromosome chr7
Pig SNP position 78947487
2.Annotation Information
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCognitive decline rate in late mild cognitive impairment
Initial sample472 European ancestry cases, 47 cases
Replication sampleNA
Region14q12
Chromosome idchr14
Chromosome position25552779
Reported geneSTXBP6, NOVA1
Mapped geneHMGN2P6 - LOC105370416
Upstream gene id643872
Downstream gene id105370416
SNP gene ids
Upstream gene distance285333
Downstream gene distance275002
SNP risk allelers12435940-A
SNPsrs12435940
Merged
SNP id current12435940
Contextintergenic_variant
Intergenic1
Allele frequency0.96
P value0.0000004
Pvalue mlog6.39794000867203
P value text
Or beta0.485
%95 Ci[0.3-0.67] unit decrease
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitcognitive impairment, cognitive decline measurement
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0100543, http://www.ebi.ac.uk/efo/EFO_0007710
Study accessionGCST003075