SNP Detail For rs12427353
1.Mapping Information
Human SNP ID rs12427353
Human chromosome chr12
Human SNP position 120989098
Pig chromosome chr14
Pig SNP position 43391753
2.Annotation Information
PubMed ID24509480
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24509480
StudyGenome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Disease/TraitType 2 diabetes
Initial sample12,171 European ancestry cases, 56,862 European ancestry controls, 6,952 East Asian ancestry cases, 11,865 East Asian ancestry controls, 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls, 1,804 Mexican ancestry cases, 779 Mexican ance
Replication sample21,491 European ancestry cases, 55,647 European ancestry controls
Region12q24.31
Chromosome idchr12
Chromosome position120989098
Reported geneHNF1A
Mapped geneHNF1A
Upstream gene id
Downstream gene id
SNP gene ids6927
Upstream gene distance
Downstream gene distance
SNP risk allelers12427353-G
SNPsrs12427353
Merged0
SNP id current12427353
Contextintron_variant
Intergenic0
Allele frequency0.77
P value0.000004
Pvalue mlog5.39794000867203
P value text
Or beta1.12
%95 Ci[1.07-1.18]
PlatformAffymetrix, Illumina [2500000] (imputed)
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST002352