Human SNP ID | rs12424086 |
---|---|
Human chromosome | chr12 |
Human SNP position | 65970729 |
Pig chromosome | chr5 |
Pig SNP position | 33527546 |
PubMed ID | 21931568 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21931568 |
Study | Genome-wide association study identifies four loci associated with eruption of permanent teeth. |
Disease/Trait | Permanent tooth development |
Initial sample | 5,088 European ancestry females |
Replication sample | 2,994 European ancestry individuals, 161 individuals |
Region | 12q14.3 |
Chromosome id | chr12 |
Chromosome position | 65970729 |
Reported gene | HMGA2 |
Mapped gene | HMGA2 - MIR6074 |
Upstream gene id | 8091 |
Downstream gene id | 102464827 |
SNP gene ids | |
Upstream gene distance | 4438 |
Downstream gene distance | 52891 |
SNP risk allele | rs12424086-C |
SNPs | rs12424086 |
Merged | 0 |
SNP id current | 12424086 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.18 |
P value | 0.000000000002 |
Pvalue mlog | 11.698970004336 |
P value text | |
Or beta | 0.111 |
%95 Ci | [0.08-0.14] unit decrease |
Platform | Illumina [521741] |
CNV | N |
Mapped trait | tooth eruption |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0044691 |
Study accession | GCST001221 |
PubMed ID | 20195514 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20195514 |
Study | Genome-wide association study reveals multiple loci associated with primary tooth development during infancy. |
Disease/Trait | Primary tooth development (time to first tooth eruption) |
Initial sample | 5,919 European ancestry related individuals |
Replication sample | NA |
Region | 12q14.3 |
Chromosome id | chr12 |
Chromosome position | 65970729 |
Reported gene | HMGA2 |
Mapped gene | HMGA2 - MIR6074 |
Upstream gene id | 8091 |
Downstream gene id | 102464827 |
SNP gene ids | |
Upstream gene distance | 4438 |
Downstream gene distance | 52891 |
SNP risk allele | rs12424086-C |
SNPs | rs12424086 |
Merged | 0 |
SNP id current | 12424086 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.23 |
P value | 0.000008 |
Pvalue mlog | 5.09691001300805 |
P value text | |
Or beta | 0.29 |
%95 Ci | [NR] % variance |
Platform | Illumina [300766] |
CNV | N |
Mapped trait | odontogenesis |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0042476 |
Study accession | GCST000609 |
PubMed ID | 20195514 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20195514 |
Study | Genome-wide association study reveals multiple loci associated with primary tooth development during infancy. |
Disease/Trait | Primary tooth development (number of teeth) |
Initial sample | 5,752 European ancestry related individuals |
Replication sample | NA |
Region | 12q14.3 |
Chromosome id | chr12 |
Chromosome position | 65970729 |
Reported gene | HMGA2 |
Mapped gene | HMGA2 - MIR6074 |
Upstream gene id | 8091 |
Downstream gene id | 102464827 |
SNP gene ids | |
Upstream gene distance | 4438 |
Downstream gene distance | 52891 |
SNP risk allele | rs12424086-C |
SNPs | rs12424086 |
Merged | 0 |
SNP id current | 12424086 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.23 |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | |
Or beta | 0.22 |
%95 Ci | % variance |
Platform | Illumina [300766] |
CNV | N |
Mapped trait | odontogenesis |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0042476 |
Study accession | GCST000610 |