SNP Detail For rs12421382
1.Mapping Information
Human SNP ID rs12421382
Human chromosome chr11
Human SNP position 109507345
Pig chromosome chr9
Pig SNP position 42052710
2.Annotation Information
PubMed ID25056061
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25056061
StudyBiological insights from 108 schizophrenia-associated genetic loci.
Disease/TraitSchizophrenia
Initial sample32,405 European ancestry cases, 42,221 European ancestry controls, 1,235 European ancestry cases and 1,235 European ancestry controls from 1235 parent-offspring trios, 1,836 East Asian ancestry cases, 3,383 East Asian ancestry controls
Replication sample1,513 European ancestry cases, 66,236 European ancestry controls
Region11q22.3
Chromosome idchr11
Chromosome position109507345
Reported geneC11orf87
Mapped geneC11orf87 - LOC105369481
Upstream gene id399947
Downstream gene id105369481
SNP gene ids
Upstream gene distance78178
Downstream gene distance234322
SNP risk allelers12421382-C
SNPsrs12421382
Merged0
SNP id current12421382
Contextintron_variant
Intergenic1
Allele frequency0.666
P value0.00000004
Pvalue mlog7.39794000867203
P value text
Or beta1.0626993
%95 Ci[1.04-1.09]
PlatformAffymetrix, Illumina [9005918] (imputed)
CNVN
Mapped traitschizophrenia
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000692
Study accessionGCST002539
PubMed ID26198764
JournalAm J Med Genet B Neuropsychiatr Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26198764
StudyGenome-wide association study of schizophrenia in Ashkenazi Jews.
Disease/TraitSchizophrenia
Initial sample592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls
Replication sampleNA
Region11q22.3
Chromosome idchr11
Chromosome position109507345
Reported geneNR
Mapped geneC11orf87 - LOC105369481
Upstream gene id399947
Downstream gene id105369481
SNP gene ids
Upstream gene distance78178
Downstream gene distance234322
SNP risk allelers12421382-C
SNPsrs12421382
Merged0
SNP id current12421382
Contextintron_variant
Intergenic1
Allele frequencyNR
P value0.00000004
Pvalue mlog7.39794000867203
P value text
Or beta1.0638298
%95 Ci[NR]
PlatformIllumina [7158791] (imputed)
CNVN
Mapped traitschizophrenia
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000692
Study accessionGCST003048