SNP Detail For rs12418451
1.Mapping Information
Human SNP ID rs12418451
Human chromosome chr11
Human SNP position 69167951
Pig chromosome chr2
Pig SNP position 2544520
2.Annotation Information
PubMed ID22219177
JournalCarcinogenesis
Linkwww.ncbi.nlm.nih.gov/pubmed/22219177
StudyA genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.
Disease/TraitProstate cancer (gene x gene interaction)
Initial sample4,723 European ancestry cases, 4,792 European ancestry controls
Replication sampleNA
Region14q11.2 x 11q13.3
Chromosome idchr14 x 11
Chromosome position20556460 x 69167951
Reported geneRNASE9 x MYEOV
Mapped geneRNASE9 x LOC338694, LOC105369366
Upstream gene id
Downstream gene id
SNP gene ids
Upstream gene distance
Downstream gene distance
SNP risk allelers1243647-? x rs12418451-?
SNPsrs1243647 x rs12418451
Merged
SNP id current
Contextmissense_variant x intron_variant
Intergenic
Allele frequencyNR
P value0.000001
Pvalue mlog6
P value text
Or beta1.3333
%95 Ci[1.19-1.49]
PlatformAffymetrix, Illumina [1117531] (imputed)
CNVN
Mapped traitprostate carcinoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001663
Study accessionGCST001370
PubMed ID22219177
JournalCarcinogenesis
Linkwww.ncbi.nlm.nih.gov/pubmed/22219177
StudyA genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.
Disease/TraitProstate cancer (gene x gene interaction)
Initial sample4,723 European ancestry cases, 4,792 European ancestry controls
Replication sampleNA
Region15q21.1 x 11q13.3
Chromosome idchr15 x 11
Chromosome position48747600 x 69167951
Reported geneCEP152 x MYEOV
Mapped geneCEP152 x LOC338694, LOC105369366
Upstream gene id
Downstream gene id
SNP gene ids
Upstream gene distance
Downstream gene distance
SNP risk allelers784411-? x rs12418451-?
SNPsrs784411 x rs12418451
Merged
SNP id current
Contextintron_variant x intron_variant
Intergenic
Allele frequencyNR
P value0.0000001
Pvalue mlog7
P value text
Or beta1.42
%95 Ci[1.25-1.61]
PlatformAffymetrix, Illumina [1117531] (imputed)
CNVN
Mapped traitprostate carcinoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001663
Study accessionGCST001370
PubMed ID22219177
JournalCarcinogenesis
Linkwww.ncbi.nlm.nih.gov/pubmed/22219177
StudyA genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.
Disease/TraitProstate cancer (gene x gene interaction)
Initial sample4,723 European ancestry cases, 4,792 European ancestry controls
Replication sampleNA
Region3p14.3 x 11q13.3
Chromosome idchr3 x 11
Chromosome position57409039 x 69167951
Reported geneDNAH12 x MYEOV
Mapped geneDNAH12 x LOC338694, LOC105369366
Upstream gene id
Downstream gene id
SNP gene ids
Upstream gene distance
Downstream gene distance
SNP risk allelers1916284-? x rs12418451-?
SNPsrs1916284 x rs12418451
Merged
SNP id current
Contextintron_variant x intron_variant
Intergenic
Allele frequencyNR
P value0.000001
Pvalue mlog6
P value text
Or beta1.2658
%95 Ci[1.15-1.41]
PlatformAffymetrix, Illumina [1117531] (imputed)
CNVN
Mapped traitprostate carcinoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001663
Study accessionGCST001370