SNP Detail For rs12416687
1.Mapping Information
Human SNP ID rs12416687
Human chromosome chr10
Human SNP position 102869254
Pig chromosome chr14
Pig SNP position 123816275
2.Annotation Information
PubMed ID24954895
JournalAm J Hum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24954895
StudyGene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia.
Disease/TraitBlood pressure
Initial sample55,796 European ancestry individuals
Replication sample43,445 European ancestry individuals, 1,849 Chinese ancestry individuals, 2,502 Malay ancestry individuals, 2,476 Asian Indian ancestry individuals, 1,855 Asian ancestry individuals
Region10q24.32
Chromosome idchr10
Chromosome position102869254
Reported geneAS3MT
Mapped geneLOC105378462, C10orf32-ASMT
Upstream gene id
Downstream gene id
SNP gene ids105378462, 100528007
Upstream gene distance
Downstream gene distance
SNP risk allelers12416687-T
SNPsrs12416687
Merged0
SNP id current12416687
Contextintron_variant
Intergenic0
Allele frequency
P value0.000000004
Pvalue mlog8.39794000867203
P value text(EA, MAP, Age 50-59)
Or beta0.59
%95 Ci[0.39-0.79] mmHg decrease
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitmean arterial pressure
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006340
Study accessionGCST002497