SNP Detail For rs12409794
1.Mapping Information
Human SNP ID rs12409794
Human chromosome chr1
Human SNP position 108041481
Pig chromosome chr4
Pig SNP position 122321725
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region1p13.3
Chromosome idchr1
Chromosome position108041481
Reported geneIntergenic
Mapped geneVAV3-AS1 - LOC107985124
Upstream gene id100873946
Downstream gene id107985124
SNP gene ids
Upstream gene distance46874
Downstream gene distance22913
SNP risk allelers12409794-A
SNPsrs12409794
Merged0
SNP id current12409794
Contextintron_variant
Intergenic1
Allele frequency0.09
P value0.00000007
Pvalue mlog7.15490195998574
P value text
Or beta0.09
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region1p13.3
Chromosome idchr1
Chromosome position108041481
Reported geneIntergenic
Mapped geneVAV3-AS1 - LOC107985124
Upstream gene id100873946
Downstream gene id107985124
SNP gene ids
Upstream gene distance46874
Downstream gene distance22913
SNP risk allelers12409794-A
SNPsrs12409794
Merged0
SNP id current12409794
Contextintron_variant
Intergenic1
Allele frequency0.089
P value0.000004
Pvalue mlog5.39794000867203
P value text
Or beta0.016
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264