SNP Detail For rs12310399
1.Mapping Information
Human SNP ID rs12310399
Human chromosome chr12
Human SNP position 95096472
Pig chromosome chr5
Pig SNP position 92458385
2.Annotation Information
PubMed ID23648065
JournalCancer Sci
Linkwww.ncbi.nlm.nih.gov/pubmed/23648065
StudyGenome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Disease/TraitAdverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)
Initial sample150 Japanese ancestry cases, 166 Japanese ancestry controls
Replication sampleNA
Region12q22
Chromosome idchr12
Chromosome position95096472
Reported geneFGD6
Mapped geneFGD6
Upstream gene id
Downstream gene id
SNP gene ids55785
Upstream gene distance
Downstream gene distance
SNP risk allelers12310399-A
SNPsrs12310399
Merged0
SNP id current12310399
Contextintron_variant
Intergenic0
Allele frequency0.567
P value0.0000002
Pvalue mlog6.69897000433601
P value text(Recessive model)
Or beta1.852
%95 Ci[1.329-2.58]
PlatformIllumina [733202]
CNVN
Mapped traitresponse to carboplatin, response to paclitaxel, response to antineoplastic agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097328, http://purl.obolibrary.org/obo/GO_1901555, http://purl.obolibrary.org/obo/GO_0097327
Study accessionGCST002006