Human SNP ID | rs12310399 |
---|---|
Human chromosome | chr12 |
Human SNP position | 95096472 |
Pig chromosome | chr5 |
Pig SNP position | 92458385 |
PubMed ID | 23648065 |
---|---|
Journal | Cancer Sci |
Link | www.ncbi.nlm.nih.gov/pubmed/23648065 |
Study | Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. |
Disease/Trait | Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin) |
Initial sample | 150 Japanese ancestry cases, 166 Japanese ancestry controls |
Replication sample | NA |
Region | 12q22 |
Chromosome id | chr12 |
Chromosome position | 95096472 |
Reported gene | FGD6 |
Mapped gene | FGD6 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 55785 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs12310399-A |
SNPs | rs12310399 |
Merged | 0 |
SNP id current | 12310399 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.567 |
P value | 0.0000002 |
Pvalue mlog | 6.69897000433601 |
P value text | (Recessive model) |
Or beta | 1.852 |
%95 Ci | [1.329-2.58] |
Platform | Illumina [733202] |
CNV | N |
Mapped trait | response to carboplatin, response to paclitaxel, response to antineoplastic agent |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0097328, http://purl.obolibrary.org/obo/GO_1901555, http://purl.obolibrary.org/obo/GO_0097327 |
Study accession | GCST002006 |