SNP Detail For rs12145922
1.Mapping Information
Human SNP ID rs12145922
Human chromosome chr1
Human SNP position 88680551
Pig chromosome chr4
Pig SNP position 139938786
2.Annotation Information
PubMed ID22001757
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22001757
StudyGenome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
Disease/TraitLiver enzyme levels (gamma-glutamyl transferase)
Initial sampleUp to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals
Replication sampleNA
Region1p22.2
Chromosome idchr1
Chromosome position88680551
Reported geneCCBL2, PKN2
Mapped genePKN2-AS1
Upstream gene id
Downstream gene id
SNP gene ids101927891
Upstream gene distance
Downstream gene distance
SNP risk allelers12145922-A
SNPsrs12145922
Merged0
SNP id current12145922
Contextintron_variant
Intergenic0
Allele frequency0.61
P value0.00000000004
Pvalue mlog10.397940008672
P value text
Or beta2.8
%95 Ci[2.20-3.40] % increase
PlatformAffymetrix, Illumina, Perlegen [~ 2600000] (imputed)
CNVN
Mapped traitserum gamma-glutamyl transferase measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004532
Study accessionGCST001277