SNP Detail For rs12142335
1.Mapping Information
Human SNP ID rs12142335
Human chromosome chr1
Human SNP position 107760300
Pig chromosome chr4
Pig SNP position 122762410
2.Annotation Information
PubMed ID23648065
JournalCancer Sci
Linkwww.ncbi.nlm.nih.gov/pubmed/23648065
StudyGenome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Disease/TraitAdverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)
Initial sample176 Japanese ancestry cases, 471 Japanese ancestry controls
Replication sampleNA
Region1p13.3
Chromosome idchr1
Chromosome position107760300
Reported geneVAV3
Mapped geneVAV3
Upstream gene id
Downstream gene id
SNP gene ids10451
Upstream gene distance
Downstream gene distance
SNP risk allelers12142335-A
SNPsrs12142335
Merged0
SNP id current12142335
Contextintron_variant
Intergenic0
Allele frequency0.004
P value0.000008
Pvalue mlog5.09691001300805
P value text(Dominant model)
Or beta9.713
%95 Ci[3.175-29.71]
PlatformIllumina [733202]
CNVN
Mapped traitresponse to cisplatin, response to antineoplastic agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0072718, http://purl.obolibrary.org/obo/GO_0097327
Study accessionGCST002007