Human SNP ID | rs12142335 |
---|---|
Human chromosome | chr1 |
Human SNP position | 107760300 |
Pig chromosome | chr4 |
Pig SNP position | 122762410 |
PubMed ID | 23648065 |
---|---|
Journal | Cancer Sci |
Link | www.ncbi.nlm.nih.gov/pubmed/23648065 |
Study | Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. |
Disease/Trait | Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) |
Initial sample | 176 Japanese ancestry cases, 471 Japanese ancestry controls |
Replication sample | NA |
Region | 1p13.3 |
Chromosome id | chr1 |
Chromosome position | 107760300 |
Reported gene | VAV3 |
Mapped gene | VAV3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10451 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs12142335-A |
SNPs | rs12142335 |
Merged | 0 |
SNP id current | 12142335 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.004 |
P value | 0.000008 |
Pvalue mlog | 5.09691001300805 |
P value text | (Dominant model) |
Or beta | 9.713 |
%95 Ci | [3.175-29.71] |
Platform | Illumina [733202] |
CNV | N |
Mapped trait | response to cisplatin, response to antineoplastic agent |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0072718, http://purl.obolibrary.org/obo/GO_0097327 |
Study accession | GCST002007 |