Human SNP ID | rs12053903 |
---|---|
Human chromosome | chr3 |
Human SNP position | 38551902 |
Pig chromosome | chr13 |
Pig SNP position | 25519768 |
PubMed ID | 19305408 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19305408 |
Study | Common variants at ten loci influence QT interval duration in the QTGEN Study. |
Disease/Trait | QT interval |
Initial sample | 13,685 European ancestry individuals |
Replication sample | 15,854 European ancestry individuals |
Region | 3p22.2 |
Chromosome id | chr3 |
Chromosome position | 38551902 |
Reported gene | SCN5A |
Mapped gene | SCN5A |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6331 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs12053903-C |
SNPs | rs12053903 |
Merged | 0 |
SNP id current | 12053903 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.34 |
P value | 0.00000000000001 |
Pvalue mlog | 14 |
P value text | |
Or beta | 1.23 |
%95 Ci | [0.88-1.57] msec decrease |
Platform | Affymetrix, Illumina [up to 2543686] (imputed) |
CNV | N |
Mapped trait | QT interval |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004682 |
Study accession | GCST000363 |
PubMed ID | 20062063 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20062063 |
Study | Several common variants modulate heart rate, PR interval and QRS duration. |
Disease/Trait | Electrocardiographic traits |
Initial sample | Up to 12,670 European ancestry individuals |
Replication sample | Up to 10,352 European ancestry individuals |
Region | 3p22.2 |
Chromosome id | chr3 |
Chromosome position | 38551902 |
Reported gene | SCN5A |
Mapped gene | SCN5A |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6331 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs12053903-T |
SNPs | rs12053903 |
Merged | 0 |
SNP id current | 12053903 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.72 |
P value | 0.0000001 |
Pvalue mlog | 7 |
P value text | (PR interval) |
Or beta | 6.59 |
%95 Ci | [4.16-9.03] % s.d. decrease |
Platform | Illumina [306060] |
CNV | N |
Mapped trait | PR interval |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004462 |
Study accession | GCST000561 |