SNP Detail For rs11994937
1.Mapping Information
Human SNP ID rs11994937
Human chromosome chr8
Human SNP position 58596021
Pig chromosome chr4
Pig SNP position 81079994
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region8q12.1
Chromosome idchr8
Chromosome position58596021
Reported geneNR
Mapped geneNSMAF
Upstream gene id
Downstream gene id
SNP gene ids8439
Upstream gene distance
Downstream gene distance
SNP risk allelers11994937-C
SNPsrs11994937
Merged0
SNP id current11994937
Contextintron_variant
Intergenic0
Allele frequency0.978061912475822
P value0.000005
Pvalue mlog5.30102999566398
P value text(IGP14)
Or beta0.5011
%95 Ci[0.29-0.72] unit decrease
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848