Human SNP ID | rs11978267 |
---|---|
Human chromosome | chr7 |
Human SNP position | 50398606 |
Pig chromosome | chr9 |
Pig SNP position | 150040680 |
PubMed ID | 19684603 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19684603 |
Study | Germline genomic variants associated with childhood acute lymphoblastic leukemia. |
Disease/Trait | Acute lymphoblastic leukemia (childhood) |
Initial sample | 317 European ancestry cases, 17,958 European ancestry controls |
Replication sample | NA |
Region | 7p12.2 |
Chromosome id | chr7 |
Chromosome position | 50398606 |
Reported gene | DDC, IKZF1 |
Mapped gene | IKZF1, LOC105375275 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10320, 105375275 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11978267-G |
SNPs | rs11978267 |
Merged | 0 |
SNP id current | 11978267 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.27 |
P value | 0.00000000008 |
Pvalue mlog | 10.096910013008 |
P value text | |
Or beta | 1.69 |
%95 Ci | [1.40-1.90] |
Platform | Affymetrix [307944] |
CNV | N |
Mapped trait | acute lymphoblastic leukemia |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000220 |
Study accession | GCST000464 |
PubMed ID | 22076464 |
Journal | Leukemia |
Link | www.ncbi.nlm.nih.gov/pubmed/22076464 |
Study | Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia. |
Disease/Trait | Acute lymphoblastic leukemia (childhood) |
Initial sample | 419 European ancestry ETV6-RUNX1 positive cases, 474 European ancestry controls |
Replication sample | 951 European ancestry ETV6-RUNX1 positive cases, 326 European ancestry ETV6-RUNX1 negative cases, 3,061 European ancestry controls |
Region | 7p12.2 |
Chromosome id | chr7 |
Chromosome position | 50398606 |
Reported gene | IKZF1 |
Mapped gene | IKZF1, LOC105375275 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10320, 105375275 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11978267-G |
SNPs | rs11978267 |
Merged | 0 |
SNP id current | 11978267 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.27 |
P value | 0.00000000009 |
Pvalue mlog | 10.0457574905606 |
P value text | (ETV6-RUNX1 positive) |
Or beta | 1.43 |
%95 Ci | [1.28 - 1.59] |
Platform | Affymetrix [355750] |
CNV | N |
Mapped trait | acute lymphoblastic leukemia |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000220 |
Study accession | GCST001320 |