SNP Detail For rs11891401
1.Mapping Information
Human SNP ID rs11891401
Human chromosome chr2
Human SNP position 164230237
Pig chromosome chr15
Pig SNP position 78800593
2.Annotation Information
PubMed ID24954895
JournalAm J Hum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24954895
StudyGene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia.
Disease/TraitBlood pressure
Initial sample55,796 European ancestry individuals
Replication sample43,445 European ancestry individuals, 1,849 Chinese ancestry individuals, 2,502 Malay ancestry individuals, 2,476 Asian Indian ancestry individuals, 1,855 Asian ancestry individuals
Region2q24.3
Chromosome idchr2
Chromosome position164230237
Reported geneGRB14, FIGN
Mapped geneFIGN - GRB14
Upstream gene id55137
Downstream gene id2888
SNP gene ids
Upstream gene distance494040
Downstream gene distance262169
SNP risk allelers11891401-T
SNPsrs11891401
Merged0
SNP id current11891401
Contextintron_variant
Intergenic1
Allele frequency
P value0.000002
Pvalue mlog5.69897000433601
P value text(EA, SBP, Age 50-59)
Or beta0.67
%95 Ci[0.4-0.94] mmHg increase
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitsystolic blood pressure
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006335
Study accessionGCST002497