SNP Detail For rs117767473
1.Mapping Information
Human SNP ID rs117767473
Human chromosome chr11
Human SNP position 70480488
Pig chromosome chr2
Pig SNP position 1241733
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region11q13.3
Chromosome idchr11
Chromosome position70480488
Reported geneBC127192
Mapped geneSHANK2
Upstream gene id
Downstream gene id
SNP gene ids22941
Upstream gene distance
Downstream gene distance
SNP risk allelers117767473-A
SNPsrs117767473
Merged0
SNP id current117767473
Contextintron_variant
Intergenic0
Allele frequency0.999
P value0.00000002
Pvalue mlog7.69897000433601
P value text(AA)
Or beta2.856
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region11q13.3
Chromosome idchr11
Chromosome position70480488
Reported geneBC127192
Mapped geneSHANK2
Upstream gene id
Downstream gene id
SNP gene ids22941
Upstream gene distance
Downstream gene distance
SNP risk allelers117767473-A
SNPsrs117767473
Merged0
SNP id current117767473
Contextintron_variant
Intergenic0
Allele frequency0.999
P value0.000003
Pvalue mlog5.52287874528033
P value text(AA)
Or beta0.474
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264