SNP Detail For rs11771429
1.Mapping Information
Human SNP ID rs11771429
Human chromosome chr7
Human SNP position 153574792
Pig chromosome chr18
Pig SNP position 4496840
2.Annotation Information
PubMed ID24121790
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24121790
StudyA genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett__s esophagus.
Disease/TraitBarrett__s esophagus
Initial sample2,416 European ancestry cases, 3,206 European ancestry controls
Replication sample759 European ancestry cases, 6,911 European ancestry controls
Region7q36.2
Chromosome idchr7
Chromosome position153574792
Reported geneNR
Mapped geneLOC105375579 - LOC105375583
Upstream gene id105375579
Downstream gene id105375583
SNP gene ids
Upstream gene distance66455
Downstream gene distance179586
SNP risk allelers11771429-G
SNPsrs11771429
Merged0
SNP id current11771429
Contextintergenic_variant
Intergenic1
Allele frequency0.816
P value0.000007
Pvalue mlog5.15490195998574
P value text
Or beta1.2195
%95 Ci[1.12-1.33]
PlatformIllumina [922031]
CNVN
Mapped traitBarrett__s esophagus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000280
Study accessionGCST002230
PubMed ID24121790
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24121790
StudyA genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett__s esophagus.
Disease/TraitDigestive system disease (Barrett__s esophagus and esophageal adenocarcinoma combined)
Initial sample3,928 European ancestry cases, 3,207 European ancestry controls
Replication sample1,636 European ancestry cases, 6,911 European ancestry controls
Region7q36.2
Chromosome idchr7
Chromosome position153574792
Reported geneNR
Mapped geneLOC105375579 - LOC105375583
Upstream gene id105375579
Downstream gene id105375583
SNP gene ids
Upstream gene distance66455
Downstream gene distance179586
SNP risk allelers11771429-G
SNPsrs11771429
Merged0
SNP id current11771429
Contextintergenic_variant
Intergenic1
Allele frequency0.816
P value0.000008
Pvalue mlog5.09691001300805
P value text
Or beta1.1905
%95 Ci[1.1-1.28]
PlatformIllumina [922031]
CNVN
Mapped traitesophageal adenocarcinoma, digestive system disease, Barrett__s esophagus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000478, http://www.ebi.ac.uk/efo/EFO_0000405, http://www.ebi.ac.uk/efo/EFO_0000280
Study accessionGCST002231