SNP Detail For rs11754288
1.Mapping Information
Human SNP ID rs11754288
Human chromosome chr6
Human SNP position 25776721
Pig chromosome chr7
Pig SNP position 21815293
2.Annotation Information
PubMed ID21943158
JournalBMC Med Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21943158
StudyGenetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.
Disease/TraitCardiovascular disease risk factors
Initial sample11,683 European ancestry individuals
Replication sampleNA
Region6p22.2
Chromosome idchr6
Chromosome position25776721
Reported geneSLC17A4
Mapped geneSLC17A4
Upstream gene id
Downstream gene id
SNP gene ids10050
Upstream gene distance
Downstream gene distance
SNP risk allelers11754288-A
SNPsrs11754288
Merged0
SNP id current11754288
Contextmissense_variant
Intergenic0
Allele frequency0.43
P value0.000000004
Pvalue mlog8.39794000867203
P value text(UA)
Or beta0.084
%95 Ci[0.057-0.111] umol/l decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traituric acid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004761
Study accessionGCST001247
PubMed ID24816252
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24816252
StudyAn atlas of genetic influences on human blood metabolites.
Disease/TraitBlood metabolite levels
Initial sample7,824 European ancestry individuals
Replication sampleNA
Region6p22.2
Chromosome idchr6
Chromosome position25776721
Reported geneSLC17A3
Mapped geneSLC17A4
Upstream gene id
Downstream gene id
SNP gene ids10050
Upstream gene distance
Downstream gene distance
SNP risk allelers11754288-A
SNPsrs11754288
Merged0
SNP id current11754288
Contextmissense_variant
Intergenic0
Allele frequency0.44
P value0.000000000002
Pvalue mlog11.698970004336
P value text(X-11469)
Or beta0.043
%95 Ci[0.031-0.055] unit increase
PlatformAffymetrix, Illumina [2100000] (imputed)
CNVN
Mapped traitblood metabolite measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005664
Study accessionGCST002443