SNP Detail For rs117526668
1.Mapping Information
Human SNP ID rs117526668
Human chromosome chr11
Human SNP position 44263881
Pig chromosome chr2
Pig SNP position 19691882
2.Annotation Information
PubMed ID25461247
JournalPharmacogenet Genomics
Linkwww.ncbi.nlm.nih.gov/pubmed/25461247
StudyGenome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols.
Disease/TraitResponse to abacavir-containing treatment in HIV-1 infection (virologic failure)
Initial sampleUp 346 European ancestry individuals, Up to 265 Black individuals, Up to 175 Hispanic individuals
Replication sampleNA
Region11p11.2
Chromosome idchr11
Chromosome position44263881
Reported geneNR
Mapped geneALX4
Upstream gene id
Downstream gene id
SNP gene ids60529
Upstream gene distance
Downstream gene distance
SNP risk allelers117526668-T
SNPsrs117526668
Merged0
SNP id current117526668
Context3_prime_UTR_variant
Intergenic0
Allele frequencyNR
P value0.000009
Pvalue mlog5.04575749056067
P value text(phenotype 3)
Or beta3.19
%95 Ci[NR]
PlatformIllumina [> 8000000] (imputed)
CNVN
Mapped traitHIV-1 infection, virologic response measurement, response to abacavir
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0006906, http://www.ebi.ac.uk/efo/EFO_0006905
Study accessionGCST002769
PubMed ID25461247
JournalPharmacogenet Genomics
Linkwww.ncbi.nlm.nih.gov/pubmed/25461247
StudyGenome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols.
Disease/TraitResponse to efavirenz-containing treatment in HIV 1 infection (virologic failure)
Initial sampleUp to 737 European ancestry individuals, Up to 545 Black individuals, Up to 314 Hispanic individuals
Replication sampleNA
Region11p11.2
Chromosome idchr11
Chromosome position44263881
Reported geneNR
Mapped geneALX4
Upstream gene id
Downstream gene id
SNP gene ids60529
Upstream gene distance
Downstream gene distance
SNP risk allelers117526668-T
SNPsrs117526668
Merged0
SNP id current117526668
Context3_prime_UTR_variant
Intergenic0
Allele frequencyNR
P value0.000009
Pvalue mlog5.04575749056067
P value text(phenotype 1)
Or beta3.19
%95 Ci[NR]
PlatformIllumina [> 8000000] (imputed)
CNVN
Mapped traitHIV-1 infection, response to efavirenz, virologic response measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0006904, http://www.ebi.ac.uk/efo/EFO_0006906
Study accessionGCST002771