PigVar
Overview
Pig SNPs
SNP Table
SNP Hit on Gene
SNP Coding
SNP lincRNA
Search SNPs by Region
Browse on Chromosome
SV
Positive Selection
Help
Manual
Pipeline
Data Statistics
Contact Us
Download
SNP Detail For rs1173771
1.Mapping Information
| Human SNP ID | rs1173771 |
|---|---|
| Human chromosome | chr5 |
| Human SNP position | 32814922 |
| Pig chromosome | chr16 |
| Pig SNP position | 19540442 |
2.Annotation Information
| PubMed ID | 21909110 |
|---|---|
| Journal | Nat Genet |
| Link | www.ncbi.nlm.nih.gov/pubmed/21909110 |
| Study | Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. |
| Disease/Trait | Blood pressure |
| Initial sample | 74,064 European ancestry individuals |
| Replication sample | 48,607 European ancestry individuals |
| Region | 5p13.3 |
| Chromosome id | chr5 |
| Chromosome position | 32814922 |
| Reported gene | C5orf23, NPR3 |
| Mapped gene | NPR3 - LOC340113 |
| Upstream gene id | 4883 |
| Downstream gene id | 340113 |
| SNP gene ids | |
| Upstream gene distance | 23198 |
| Downstream gene distance | 132521 |
| SNP risk allele | rs1173771-G |
| SNPs | rs1173771 |
| Merged | 0 |
| SNP id current | 1173771 |
| Context | regulatory_region_variant |
| Intergenic | 1 |
| Allele frequency | 0.53 |
| P value | 0.000000004 |
| Pvalue mlog | 8.39794000867203 |
| P value text | (Mean Arterial Pressure) |
| Or beta | 0.283 |
| %95 Ci | [0.19-0.37] mmHg increase |
| Platform | Affymetrix, Illumina, Perlegen [NR] (imputed) |
| CNV | N |
| Mapped trait | mean arterial pressure |
| Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006340 |
| Study accession | GCST001236 |
| PubMed ID | 21909110 |
| Journal | Nat Genet |
| Link | www.ncbi.nlm.nih.gov/pubmed/21909110 |
| Study | Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. |
| Disease/Trait | Blood pressure |
| Initial sample | 74,064 European ancestry individuals |
| Replication sample | 48,607 European ancestry individuals |
| Region | 5p13.3 |
| Chromosome id | chr5 |
| Chromosome position | 32814922 |
| Reported gene | C5orf23, NPR3 |
| Mapped gene | NPR3 - LOC340113 |
| Upstream gene id | 4883 |
| Downstream gene id | 340113 |
| SNP gene ids | |
| Upstream gene distance | 23198 |
| Downstream gene distance | 132521 |
| SNP risk allele | rs1173771-G |
| SNPs | rs1173771 |
| Merged | 0 |
| SNP id current | 1173771 |
| Context | regulatory_region_variant |
| Intergenic | 1 |
| Allele frequency | 0.53 |
| P value | 0.000000005 |
| Pvalue mlog | 8.30102999566398 |
| P value text | (Pulse Pressure) |
| Or beta | 0.276 |
| %95 Ci | [0.18-0.37] mmHg increase |
| Platform | Affymetrix, Illumina, Perlegen [NR] (imputed) |
| CNV | N |
| Mapped trait | pulse pressure measurement |
| Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005763 |
| Study accession | GCST001235 |
| PubMed ID | 21909115 |
| Journal | Nature |
| Link | www.ncbi.nlm.nih.gov/pubmed/21909115 |
| Study | Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. |
| Disease/Trait | Diastolic blood pressure |
| Initial sample | 69,395 European ancestry individuals |
| Replication sample | Up to 133,361 European ancestry individuals |
| Region | 5p13.3 |
| Chromosome id | chr5 |
| Chromosome position | 32814922 |
| Reported gene | C5orf23, NPR3 |
| Mapped gene | NPR3 - LOC340113 |
| Upstream gene id | 4883 |
| Downstream gene id | 340113 |
| SNP gene ids | |
| Upstream gene distance | 23198 |
| Downstream gene distance | 132521 |
| SNP risk allele | rs1173771-G |
| SNPs | rs1173771 |
| Merged | 0 |
| SNP id current | 1173771 |
| Context | regulatory_region_variant |
| Intergenic | 1 |
| Allele frequency | 0.6 |
| P value | 0.000000000009 |
| Pvalue mlog | 11.0457574905606 |
| P value text | |
| Or beta | 0.261 |
| %95 Ci | [NR] mmHg increase |
| Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
| CNV | N |
| Mapped trait | diastolic blood pressure |
| Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006336 |
| Study accession | GCST001228 |
| PubMed ID | 21909115 |
| Journal | Nature |
| Link | www.ncbi.nlm.nih.gov/pubmed/21909115 |
| Study | Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. |
| Disease/Trait | Hypertension |
| Initial sample | 69,395 European ancestry individuals |
| Replication sample | Up to 133,361 European ancestry individuals |
| Region | 5p13.3 |
| Chromosome id | chr5 |
| Chromosome position | 32814922 |
| Reported gene | C5orf23, NPR3 |
| Mapped gene | NPR3 - LOC340113 |
| Upstream gene id | 4883 |
| Downstream gene id | 340113 |
| SNP gene ids | |
| Upstream gene distance | 23198 |
| Downstream gene distance | 132521 |
| SNP risk allele | rs1173771-G |
| SNPs | rs1173771 |
| Merged | 0 |
| SNP id current | 1173771 |
| Context | regulatory_region_variant |
| Intergenic | 1 |
| Allele frequency | 0.6 |
| P value | 0.0000000003 |
| Pvalue mlog | 9.52287874528033 |
| P value text | |
| Or beta | 0.062 |
| %95 Ci | [NR] unit increase |
| Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
| CNV | N |
| Mapped trait | hypertension |
| Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000537 |
| Study accession | GCST001238 |
| PubMed ID | 21909115 |
| Journal | Nature |
| Link | www.ncbi.nlm.nih.gov/pubmed/21909115 |
| Study | Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. |
| Disease/Trait | Systolic blood pressure |
| Initial sample | 69,395 European ancestry individuals |
| Replication sample | Up to 133,361 European ancestry individuals |
| Region | 5p13.3 |
| Chromosome id | chr5 |
| Chromosome position | 32814922 |
| Reported gene | C5orf23, NPR3 |
| Mapped gene | NPR3 - LOC340113 |
| Upstream gene id | 4883 |
| Downstream gene id | 340113 |
| SNP gene ids | |
| Upstream gene distance | 23198 |
| Downstream gene distance | 132521 |
| SNP risk allele | rs1173771-G |
| SNPs | rs1173771 |
| Merged | 0 |
| SNP id current | 1173771 |
| Context | regulatory_region_variant |
| Intergenic | 1 |
| Allele frequency | 0.6 |
| P value | 0.0000000000000002 |
| Pvalue mlog | 15.698970004336 |
| P value text | |
| Or beta | 0.504 |
| %95 Ci | [NR] mmHg increase |
| Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
| CNV | N |
| Mapped trait | systolic blood pressure |
| Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006335 |
| Study accession | GCST001227 |
| PubMed ID | 26390057 |
| Journal | Nat Genet |
| Link | www.ncbi.nlm.nih.gov/pubmed/26390057 |
| Study | Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. |
| Disease/Trait | Mean arterial pressure |
| Initial sample | 31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals |
| Replication sample | 87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals and 16,328 South Asian ancestry individuals |
| Region | 5p13.3 |
| Chromosome id | chr5 |
| Chromosome position | 32814922 |
| Reported gene | NPR3, C5orf23 |
| Mapped gene | NPR3 - LOC340113 |
| Upstream gene id | 4883 |
| Downstream gene id | 340113 |
| SNP gene ids | |
| Upstream gene distance | 23198 |
| Downstream gene distance | 132521 |
| SNP risk allele | rs1173771-A |
| SNPs | rs1173771 |
| Merged | 0 |
| SNP id current | 1173771 |
| Context | regulatory_region_variant |
| Intergenic | 1 |
| Allele frequency | 0.3943 |
| P value | 0.00000003 |
| Pvalue mlog | 7.52287874528033 |
| P value text | |
| Or beta | 0.3486 |
| %95 Ci | [0.23-0.47] mmHg decrease |
| Platform | Affymetrix, Illumina, Perlegen [~ 2100000] (imputed) |
| CNV | N |
| Mapped trait | mean arterial pressure |
| Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006340 |
| Study accession | GCST003275 |
| PubMed ID | 26390057 |
| Journal | Nat Genet |
| Link | www.ncbi.nlm.nih.gov/pubmed/26390057 |
| Study | Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. |
| Disease/Trait | Mean arterial pressure |
| Initial sample | 31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals |
| Replication sample | 87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals and 16,328 South Asian ancestry individuals |
| Region | 5p13.3 |
| Chromosome id | chr5 |
| Chromosome position | 32814922 |
| Reported gene | NPR3, C5orf23 |
| Mapped gene | NPR3 - LOC340113 |
| Upstream gene id | 4883 |
| Downstream gene id | 340113 |
| SNP gene ids | |
| Upstream gene distance | 23198 |
| Downstream gene distance | 132521 |
| SNP risk allele | rs1173771-A |
| SNPs | rs1173771 |
| Merged | 0 |
| SNP id current | 1173771 |
| Context | regulatory_region_variant |
| Intergenic | 1 |
| Allele frequency | 0.3703 |
| P value | 0.0000003 |
| Pvalue mlog | 6.52287874528033 |
| P value text | (East Asians) |
| Or beta | 0.5853 |
| %95 Ci | [0.36-0.81] mmHg decrease |
| Platform | Affymetrix, Illumina, Perlegen [~ 2100000] (imputed) |
| CNV | N |
| Mapped trait | mean arterial pressure |
| Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006340 |
| Study accession | GCST003275 |
| PubMed ID | 26390057 |
| Journal | Nat Genet |
| Link | www.ncbi.nlm.nih.gov/pubmed/26390057 |
| Study | Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. |
| Disease/Trait | Diastolic blood pressure |
| Initial sample | 31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals |
| Replication sample | 87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals, 16,328 South Asian ancestry individuals |
| Region | 5p13.3 |
| Chromosome id | chr5 |
| Chromosome position | 32814922 |
| Reported gene | NPR3, C5orf23 |
| Mapped gene | NPR3 - LOC340113 |
| Upstream gene id | 4883 |
| Downstream gene id | 340113 |
| SNP gene ids | |
| Upstream gene distance | 23198 |
| Downstream gene distance | 132521 |
| SNP risk allele | rs1173771-A |
| SNPs | rs1173771 |
| Merged | 0 |
| SNP id current | 1173771 |
| Context | regulatory_region_variant |
| Intergenic | 1 |
| Allele frequency | 0.3702 |
| P value | 0.000003 |
| Pvalue mlog | 5.52287874528033 |
| P value text | (East Asians) |
| Or beta | 0.4608 |
| %95 Ci | [0.27-0.65] mmHg decrease |
| Platform | Affymetrix, Illumina, Perlegen [~ 2100000] (imputed) |
| CNV | N |
| Mapped trait | diastolic blood pressure |
| Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006336 |
| Study accession | GCST003273 |
|
Kunming Institute of Zoology, CAS
and Xi'an University of Technology ©2014-2017 All Rights Reserved.
|
|