SNP Detail For rs11714574
1.Mapping Information
Human SNP ID rs11714574
Human chromosome chr3
Human SNP position 58394738
Pig chromosome chr13
Pig SNP position 44090507
2.Annotation Information
PubMed ID25461247
JournalPharmacogenet Genomics
Linkwww.ncbi.nlm.nih.gov/pubmed/25461247
StudyGenome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols.
Disease/TraitResponse to abacavir-containing treatment in HIV-1 infection (virologic failure)
Initial sampleUp 346 European ancestry individuals, Up to 265 Black individuals, Up to 175 Hispanic individuals
Replication sampleNA
Region3p14.3
Chromosome idchr3
Chromosome position58394738
Reported geneNR
Mapped genePXK
Upstream gene id
Downstream gene id
SNP gene ids54899
Upstream gene distance
Downstream gene distance
SNP risk allelers11714574-T
SNPsrs11714574
Merged0
SNP id current11714574
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000009
Pvalue mlog5.04575749056067
P value text(phenotype 1)
Or beta2.38
%95 Ci[NR]
PlatformIllumina [> 8000000] (imputed)
CNVN
Mapped traitHIV-1 infection, virologic response measurement, response to abacavir
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0006906, http://www.ebi.ac.uk/efo/EFO_0006905
Study accessionGCST002769