SNP Detail For rs11700462
1.Mapping Information
Human SNP ID rs11700462
Human chromosome chr21
Human SNP position 37445510
Pig chromosome chr13
Pig SNP position 211182243
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region21q22.13
Chromosome idchr21
Chromosome position37445510
Reported geneNR
Mapped geneDYRK1A
Upstream gene id
Downstream gene id
SNP gene ids1859
Upstream gene distance
Downstream gene distance
SNP risk allelers11700462-G
SNPsrs11700462
Merged0
SNP id current11700462
Contextintron_variant
Intergenic0
Allele frequency0.89698245367811
P value0.000005
Pvalue mlog5.30102999566398
P value text(IGP33)
Or beta0.2827
%95 Ci[0.16-0.4] unit decrease
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848