Human SNP ID | rs11676272 |
---|---|
Human chromosome | chr2 |
Human SNP position | 24918669 |
Pig chromosome | chr3 |
Pig SNP position | 121107462 |
PubMed ID | 25044758 |
---|---|
Journal | Obesity (Silver Spring) |
Link | www.ncbi.nlm.nih.gov/pubmed/25044758 |
Study | Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3. |
Disease/Trait | Height adjusted BMI |
Initial sample | 5,809 children |
Replication sample | 2,089 European ancestry children |
Region | 2p23.3 |
Chromosome id | chr2 |
Chromosome position | 24918669 |
Reported gene | ADCY3 |
Mapped gene | ADCY3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 109 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11676272-G |
SNPs | rs11676272 |
Merged | 0 |
SNP id current | 11676272 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.48 |
P value | 0.000000004 |
Pvalue mlog | 8.39794000867203 |
P value text | |
Or beta | 0.2 |
%95 Ci | [0.13-0.27] unit increase |
Platform | Illumina [2608006] (imputed) |
CNV | N |
Mapped trait | height-adjusted body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005851 |
Study accession | GCST002538 |
PubMed ID | 25953783 |
Journal | Int J Epidemiol |
Link | www.ncbi.nlm.nih.gov/pubmed/25953783 |
Study | A genome-wide association study of body mass index across early life and childhood. |
Disease/Trait | Body mass index |
Initial sample | 9,377 children and adolescents |
Replication sample | 3,918 European ancestry children and adolescents |
Region | 2p23.3 |
Chromosome id | chr2 |
Chromosome position | 24918669 |
Reported gene | ADCY3 |
Mapped gene | ADCY3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 109 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11676272-A |
SNPs | rs11676272 |
Merged | 0 |
SNP id current | 11676272 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.514 |
P value | 0.00000000001 |
Pvalue mlog | 11 |
P value text | (age 8) |
Or beta | 0.011 |
%95 Ci | [0.0071-0.0149] unit decrease |
Platform | Illumina [~ 2200000] (imputed) |
CNV | N |
Mapped trait | body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002894 |
PubMed ID | 25953783 |
Journal | Int J Epidemiol |
Link | www.ncbi.nlm.nih.gov/pubmed/25953783 |
Study | A genome-wide association study of body mass index across early life and childhood. |
Disease/Trait | Body mass index |
Initial sample | 9,377 children and adolescents |
Replication sample | 3,918 European ancestry children and adolescents |
Region | 2p23.3 |
Chromosome id | chr2 |
Chromosome position | 24918669 |
Reported gene | ADCY3 |
Mapped gene | ADCY3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 109 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11676272-A |
SNPs | rs11676272 |
Merged | 0 |
SNP id current | 11676272 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.514 |
P value | 0.0000000001 |
Pvalue mlog | 10 |
P value text | (age 1-17) |
Or beta | |
%95 Ci | |
Platform | Illumina [~ 2200000] (imputed) |
CNV | N |
Mapped trait | body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002894 |
PubMed ID | 26604143 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26604143 |
Study | Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. |
Disease/Trait | Childhood body mass index |
Initial sample | 34,744 European ancestry children |
Replication sample | 11,313 European ancestry children |
Region | 2p23.3 |
Chromosome id | chr2 |
Chromosome position | 24918669 |
Reported gene | ADCY3 |
Mapped gene | ADCY3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 109 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11676272-G |
SNPs | rs11676272 |
Merged | 0 |
SNP id current | 11676272 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.46 |
P value | 7E-23 |
Pvalue mlog | 22.1549019599857 |
P value text | |
Or beta | 0.068 |
%95 Ci | [0.054-0.082] unit increase |
Platform | Affymetrix, Illumina [2499691] (imputed) |
CNV | N |
Mapped trait | body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST003177 |