Human SNP ID | rs116688600 |
---|---|
Human chromosome | chr5 |
Human SNP position | 26746274 |
Pig chromosome | chr16 |
Pig SNP position | 14588092 |
PubMed ID | 25187353 |
---|---|
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/25187353 |
Study | Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. |
Disease/Trait | Clozapine-induced agranulocytosis |
Initial sample | 161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls |
Replication sample | NA |
Region | 5p14.1 |
Chromosome id | chr5 |
Chromosome position | 26746274 |
Reported gene | intergenic |
Mapped gene | MSNP1 - CDH9 |
Upstream gene id | 4479 |
Downstream gene id | 1007 |
SNP gene ids | |
Upstream gene distance | 832996 |
Downstream gene distance | 134326 |
SNP risk allele | rs116688600-C0.0196 |
SNPs | rs116688600 |
Merged | 0 |
SNP id current | 116688600 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.0196 |
P value | 0.000009 |
Pvalue mlog | 5.04575749056067 |
P value text | |
Or beta | 5.07 |
%95 Ci | [4.35-5.79] |
Platform | Illumina [8809853] (imputed) |
CNV | N |
Mapped trait | drug-induced agranulocytosis, response to clozapine |
Mapped trait URI | http://purl.obolibrary.org/obo/HP_0012235, http://purl.obolibrary.org/obo/GO_0097338 |
Study accession | GCST002595 |