SNP Detail For rs116688600
1.Mapping Information
Human SNP ID rs116688600
Human chromosome chr5
Human SNP position 26746274
Pig chromosome chr16
Pig SNP position 14588092
2.Annotation Information
PubMed ID25187353
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25187353
StudyClozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.
Disease/TraitClozapine-induced agranulocytosis
Initial sample161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls
Replication sampleNA
Region5p14.1
Chromosome idchr5
Chromosome position26746274
Reported geneintergenic
Mapped geneMSNP1 - CDH9
Upstream gene id4479
Downstream gene id1007
SNP gene ids
Upstream gene distance832996
Downstream gene distance134326
SNP risk allelers116688600-C0.0196
SNPsrs116688600
Merged0
SNP id current116688600
Contextintron_variant
Intergenic1
Allele frequency0.0196
P value0.000009
Pvalue mlog5.04575749056067
P value text
Or beta5.07
%95 Ci[4.35-5.79]
PlatformIllumina [8809853] (imputed)
CNVN
Mapped traitdrug-induced agranulocytosis, response to clozapine
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0012235, http://purl.obolibrary.org/obo/GO_0097338
Study accessionGCST002595