Human SNP ID | rs1165196 |
---|---|
Human chromosome | chr6 |
Human SNP position | 25812922 |
Pig chromosome | chr7 |
Pig SNP position | 21876288 |
PubMed ID | 20884846 |
---|---|
Journal | Circ Cardiovasc Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20884846 |
Study | Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. |
Disease/Trait | Urate levels |
Initial sample | 28,283 European ancestry individuals |
Replication sample | 22,054 European ancestry individuals |
Region | 6p22.2 |
Chromosome id | chr6 |
Chromosome position | 25812922 |
Reported gene | SLC17A1 |
Mapped gene | SLC17A1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6568 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1165196-G |
SNPs | rs1165196 |
Merged | 0 |
SNP id current | 1165196 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.46 |
P value | 5E-25 |
Pvalue mlog | 24.3010299956639 |
P value text | (Urate) |
Or beta | 6.21 |
%95 Ci | [5.03-7.39] umol/l decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | urate measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004531 |
Study accession | GCST000818 |
PubMed ID | 21983786 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21983786 |
Study | Identification of low-frequency variants associated with gout and serum uric acid levels. |
Disease/Trait | Serum uric acid levels |
Initial sample | 15,506 European ancestry individuals |
Replication sample | NA |
Region | 6p22.2 |
Chromosome id | chr6 |
Chromosome position | 25812922 |
Reported gene | SLC17A cluster |
Mapped gene | SLC17A1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6568 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1165196-A |
SNPs | rs1165196 |
Merged | 0 |
SNP id current | 1165196 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.492 |
P value | 0.000003 |
Pvalue mlog | 5.52287874528033 |
P value text | |
Or beta | 0.05 |
%95 Ci | [0.03-0.07] s.d. increase |
Platform | Illumina [15957390] (imputed) |
CNV | N |
Mapped trait | uric acid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004761 |
Study accession | GCST001269 |
PubMed ID | 25811787 |
Journal | PLoS One |
Link | www.ncbi.nlm.nih.gov/pubmed/25811787 |
Study | Modulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in Humans. |
Disease/Trait | Urate levels in overweight individuals |
Initial sample | up to 10,058 European ancestry male individuals, up to 7,189 European ancestry female individuals |
Replication sample | NA |
Region | 6p22.2 |
Chromosome id | chr6 |
Chromosome position | 25812922 |
Reported gene | SLC17A1, SLC17A4 |
Mapped gene | SLC17A1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6568 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1165196-G |
SNPs | rs1165196 |
Merged | 0 |
SNP id current | 1165196 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.46 |
P value | 0.000000001 |
Pvalue mlog | 9 |
P value text | (men) |
Or beta | 0.086 |
%95 Ci | [0.059-0.113] kg/m2 decrease |
Platform | Affymetrix, Illumina [at least 188473] (imputed) |
CNV | N |
Mapped trait | urate measurement, overweight body mass index status |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004531, http://www.ebi.ac.uk/efo/EFO_0005935 |
Study accession | GCST002829 |