Human SNP ID | rs11635553 |
---|---|
Human chromosome | chr15 |
Human SNP position | 73457267 |
Pig chromosome | chr7 |
Pig SNP position | 64558419 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 15q24.1 |
Chromosome id | chr15 |
Chromosome position | 73457267 |
Reported gene | NR |
Mapped gene | REC114 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 283677 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11635553-G |
SNPs | rs11635553 |
Merged | 0 |
SNP id current | 11635553 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.992804206752874 |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | (IGP74) |
Or beta | 1.0812 |
%95 Ci | [0.62-1.54] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 15q24.1 |
Chromosome id | chr15 |
Chromosome position | 73457267 |
Reported gene | NR |
Mapped gene | REC114 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 283677 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11635553-G |
SNPs | rs11635553 |
Merged | 0 |
SNP id current | 11635553 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.992814619440459 |
P value | 0.000006 |
Pvalue mlog | 5.22184874961635 |
P value text | (IGP75) |
Or beta | 1.0594 |
%95 Ci | [0.6-1.52] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 15q24.1 |
Chromosome id | chr15 |
Chromosome position | 73457267 |
Reported gene | NR |
Mapped gene | REC114 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 283677 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11635553-G |
SNPs | rs11635553 |
Merged | 0 |
SNP id current | 11635553 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.99282491474212 |
P value | 0.000009 |
Pvalue mlog | 5.04575749056067 |
P value text | (IGP76) |
Or beta | 1.0357 |
%95 Ci | [0.58-1.49] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |