SNP Detail For rs11597390
1.Mapping Information
Human SNP ID rs11597390
Human chromosome chr10
Human SNP position 100101678
Pig chromosome chr14
Pig SNP position 120673493
2.Annotation Information
PubMed ID18940312
JournalAm J Hum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/18940312
StudyPopulation-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.
Disease/TraitLiver enzyme levels
Initial sample7,751 European ancestry individuals
Replication sample1,005 European ancestry individuals, 3,669 Asian Indian ancestry individuals
Region10q24.31
Chromosome idchr10
Chromosome position100101678
Reported geneCHUK, ERLIN1, CPN1
Mapped geneLOC105378451
Upstream gene id
Downstream gene id
SNP gene ids105378451
Upstream gene distance
Downstream gene distance
SNP risk allelers11597390-A
SNPsrs11597390
Merged0
SNP id current11597390
Contextdownstream_gene_variant
Intergenic0
Allele frequency0.36
P value0.00000002
Pvalue mlog7.69897000433601
P value text(ALT)
Or beta0.04
%95 Ci[0.025-0.053] U/L decrease
PlatformAffymetrix, Illumina [up to 496032]
CNVN
Mapped traitliver enzyme measurement, serum alanine aminotransferase measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004582, http://www.ebi.ac.uk/efo/EFO_0004735
Study accessionGCST000248