Human SNP ID | rs11597390 |
---|---|
Human chromosome | chr10 |
Human SNP position | 100101678 |
Pig chromosome | chr14 |
Pig SNP position | 120673493 |
PubMed ID | 18940312 |
---|---|
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/18940312 |
Study | Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. |
Disease/Trait | Liver enzyme levels |
Initial sample | 7,751 European ancestry individuals |
Replication sample | 1,005 European ancestry individuals, 3,669 Asian Indian ancestry individuals |
Region | 10q24.31 |
Chromosome id | chr10 |
Chromosome position | 100101678 |
Reported gene | CHUK, ERLIN1, CPN1 |
Mapped gene | LOC105378451 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105378451 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11597390-A |
SNPs | rs11597390 |
Merged | 0 |
SNP id current | 11597390 |
Context | downstream_gene_variant |
Intergenic | 0 |
Allele frequency | 0.36 |
P value | 0.00000002 |
Pvalue mlog | 7.69897000433601 |
P value text | (ALT) |
Or beta | 0.04 |
%95 Ci | [0.025-0.053] U/L decrease |
Platform | Affymetrix, Illumina [up to 496032] |
CNV | N |
Mapped trait | liver enzyme measurement, serum alanine aminotransferase measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004582, http://www.ebi.ac.uk/efo/EFO_0004735 |
Study accession | GCST000248 |