SNP Detail For rs11594258
1.Mapping Information
Human SNP ID rs11594258
Human chromosome chr10
Human SNP position 77458272
Pig chromosome chr14
Pig SNP position 86397044
2.Annotation Information
PubMed ID26265699
JournalBlood
Linkwww.ncbi.nlm.nih.gov/pubmed/26265699
StudyGenetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia.
Disease/TraitGlucocorticoid-induced osteonecrosis
Initial sample274 European ancestry osteonecrosis cases, 25 Black osteonecrosis cases, 68 Hispanic osteonecrosis cases, 6 Asian ancestry osteonecrosis cases, 27 other ancestry osteonecrosis cases, 1,477 European ancestry treated controls, 223 Black treated controls, 5
Replication sampleNA
Region10q22.3
Chromosome idchr10
Chromosome position77458272
Reported geneKCNMA1
Mapped geneKCNMA1
Upstream gene id
Downstream gene id
SNP gene ids3778
Upstream gene distance
Downstream gene distance
SNP risk allelers11594258-A
SNPsrs11594258
Merged
SNP id current11594258
Contextintron_variant
Intergenic0
Allele frequency0.822
P value0.000009
Pvalue mlog5.04575749056067
P value text
Or beta
%95 Ci
PlatformAffymetrix, Illumina [NR] (imputed)
CNVN
Mapped traitresponse to glucocorticoid, osteonecrosis
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0051384, http://www.ebi.ac.uk/efo/EFO_0004259
Study accessionGCST003084