Human SNP ID | rs11594258 |
---|---|
Human chromosome | chr10 |
Human SNP position | 77458272 |
Pig chromosome | chr14 |
Pig SNP position | 86397044 |
PubMed ID | 26265699 |
---|---|
Journal | Blood |
Link | www.ncbi.nlm.nih.gov/pubmed/26265699 |
Study | Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia. |
Disease/Trait | Glucocorticoid-induced osteonecrosis |
Initial sample | 274 European ancestry osteonecrosis cases, 25 Black osteonecrosis cases, 68 Hispanic osteonecrosis cases, 6 Asian ancestry osteonecrosis cases, 27 other ancestry osteonecrosis cases, 1,477 European ancestry treated controls, 223 Black treated controls, 5 |
Replication sample | NA |
Region | 10q22.3 |
Chromosome id | chr10 |
Chromosome position | 77458272 |
Reported gene | KCNMA1 |
Mapped gene | KCNMA1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3778 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11594258-A |
SNPs | rs11594258 |
Merged | |
SNP id current | 11594258 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.822 |
P value | 0.000009 |
Pvalue mlog | 5.04575749056067 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Affymetrix, Illumina [NR] (imputed) |
CNV | N |
Mapped trait | response to glucocorticoid, osteonecrosis |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0051384, http://www.ebi.ac.uk/efo/EFO_0004259 |
Study accession | GCST003084 |