SNP Detail For rs115764752
1.Mapping Information
Human SNP ID rs115764752
Human chromosome chr1
Human SNP position 171778066
Pig chromosome chr9
Pig SNP position 125662553
2.Annotation Information
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCognitive decline rate in late mild cognitive impairment
Initial sample472 European ancestry cases, 47 cases
Replication sampleNA
Region1q24.3
Chromosome idchr1
Chromosome position171778066
Reported geneVAMP4, METTL13
Mapped geneLOC105371614
Upstream gene id
Downstream gene id
SNP gene ids105371614
Upstream gene distance
Downstream gene distance
SNP risk allelers115764752-T
SNPsrs115764752
Merged
SNP id current115764752
Contextupstream_gene_variant
Intergenic0
Allele frequency0.0046
P value0.000001
Pvalue mlog6
P value text(EA)
Or beta0.5455
%95 Ci[0.33-0.76] unit increase
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitcognitive impairment, cognitive decline measurement
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0100543, http://www.ebi.ac.uk/efo/EFO_0007710
Study accessionGCST003075
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCognitive decline rate in late mild cognitive impairment
Initial sample472 European ancestry cases, 47 cases
Replication sampleNA
Region1q24.3
Chromosome idchr1
Chromosome position171778066
Reported geneVAMP4, METTL13
Mapped geneLOC105371614
Upstream gene id
Downstream gene id
SNP gene ids105371614
Upstream gene distance
Downstream gene distance
SNP risk allelers115764752-T
SNPsrs115764752
Merged
SNP id current115764752
Contextupstream_gene_variant
Intergenic0
Allele frequency0.0046
P value0.0000007
Pvalue mlog6.15490195998574
P value text
Or beta0.5409
%95 Ci[0.33-0.75] unit increase
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitcognitive impairment, cognitive decline measurement
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0100543, http://www.ebi.ac.uk/efo/EFO_0007710
Study accessionGCST003075