SNP Detail For rs11574914
1.Mapping Information
Human SNP ID rs11574914
Human chromosome chr9
Human SNP position 34710341
Pig chromosome chr10
Pig SNP position 36233017
2.Annotation Information
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region9p13.3
Chromosome idchr9
Chromosome position34710341
Reported geneCCL19, CCL21
Mapped geneCCL21 - FAM205A
Upstream gene id6366
Downstream gene id259308
SNP gene ids
Upstream gene distance174
Downstream gene distance12712
SNP risk allelers11574914-A
SNPsrs11574914
Merged0
SNP id current11574914
Contextupstream_gene_variant
Intergenic1
Allele frequency0.33
P value0.000000000000002
Pvalue mlog14.698970004336
P value text(EA)
Or beta1.13
%95 Ci[1.09-1.16]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region9p13.3
Chromosome idchr9
Chromosome position34710341
Reported geneCCL19, CCL21
Mapped geneCCL21 - FAM205A
Upstream gene id6366
Downstream gene id259308
SNP gene ids
Upstream gene distance174
Downstream gene distance12712
SNP risk allelers11574914-A
SNPsrs11574914
Merged0
SNP id current11574914
Contextupstream_gene_variant
Intergenic1
Allele frequency0.26
P value0.000000000000003
Pvalue mlog14.5228787452803
P value text
Or beta1.12
%95 Ci[1.09-1.15]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318