SNP Detail For rs1154988
1.Mapping Information
Human SNP ID rs1154988
Human chromosome chr3
Human SNP position 136206349
Pig chromosome chr13
Pig SNP position 84554267
2.Annotation Information
PubMed ID23969696
JournalCirculation
Linkwww.ncbi.nlm.nih.gov/pubmed/23969696
StudyMultiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
Disease/TraitFibrinogen
Initial sample91,323 European ancestry individuals
Replication sample8,423 African American individuals, 1,447 Hispanic individuals
Region3q22.3
Chromosome idchr3
Chromosome position136206349
Reported geneMSL2, PCCB
Mapped geneRPL31P23 - PCCB
Upstream gene id391581
Downstream gene id5096
SNP gene ids
Upstream gene distance406
Downstream gene distance43976
SNP risk allelers1154988-A
SNPsrs1154988
Merged0
SNP id current1154988
Contextupstream_gene_variant
Intergenic1
Allele frequency0.78
P value0.0000000000000001
Pvalue mlog16
P value text(EA)
Or beta0.01
%95 Ci[0.008-0.012] unit decrease
PlatformAffymetrix, Illumina [2515567] (imputed)
CNVN
Mapped traitfibrinogen measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004623
Study accessionGCST002147