Human SNP ID | rs1154988 |
---|---|
Human chromosome | chr3 |
Human SNP position | 136206349 |
Pig chromosome | chr13 |
Pig SNP position | 84554267 |
PubMed ID | 23969696 |
---|---|
Journal | Circulation |
Link | www.ncbi.nlm.nih.gov/pubmed/23969696 |
Study | Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. |
Disease/Trait | Fibrinogen |
Initial sample | 91,323 European ancestry individuals |
Replication sample | 8,423 African American individuals, 1,447 Hispanic individuals |
Region | 3q22.3 |
Chromosome id | chr3 |
Chromosome position | 136206349 |
Reported gene | MSL2, PCCB |
Mapped gene | RPL31P23 - PCCB |
Upstream gene id | 391581 |
Downstream gene id | 5096 |
SNP gene ids | |
Upstream gene distance | 406 |
Downstream gene distance | 43976 |
SNP risk allele | rs1154988-A |
SNPs | rs1154988 |
Merged | 0 |
SNP id current | 1154988 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.78 |
P value | 0.0000000000000001 |
Pvalue mlog | 16 |
P value text | (EA) |
Or beta | 0.01 |
%95 Ci | [0.008-0.012] unit decrease |
Platform | Affymetrix, Illumina [2515567] (imputed) |
CNV | N |
Mapped trait | fibrinogen measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004623 |
Study accession | GCST002147 |