SNP Detail For rs114444506
1.Mapping Information
Human SNP ID rs114444506
Human chromosome chr11
Human SNP position 26325284
Pig chromosome chr2
Pig SNP position 36518705
2.Annotation Information
PubMed ID25344690
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25344690
StudyCommon variants associated with general and MMR vaccine-related febrile seizures.
Disease/TraitFebrile seizures
Initial sample929 European ancestry MMR vaccine-related febrile seizures cases, 1,070 European ancestry MMR vaccine-unrelated febrile seizures cases, 4,118 European ancestry controls
Replication sampleUp to 408 European ancestry MMR vaccine-related febrile seizures cases, Up to 1,034 European ancestry MMR vaccine-unrelated febrile seizures cases, Up to 1,645 European ancestry controls
Region11p14.2
Chromosome idchr11
Chromosome position26325284
Reported geneANO3
Mapped geneANO3
Upstream gene id
Downstream gene id
SNP gene ids63982
Upstream gene distance
Downstream gene distance
SNP risk allelers114444506-C
SNPsrs114444506
Merged0
SNP id current114444506
Contextintron_variant
Intergenic0
Allele frequency0.028
P value4E-20
Pvalue mlog19.397940008672
P value text(Overall)
Or beta2.09
%95 Ci[1.79-2.44]
PlatformIllumina [up to 8129553] (imputed)
CNVN
Mapped traitfebrile seizures
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0002373
Study accessionGCST002672
PubMed ID25344690
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25344690
StudyCommon variants associated with general and MMR vaccine-related febrile seizures.
Disease/TraitFebrile seizures (MMR vaccine-related)
Initial sample929 European ancestry cases, 4,118 European ancestry controls
Replication sampleUp to 408 European ancestry cases, Up to 1,645 European ancestry controls
Region11p14.2
Chromosome idchr11
Chromosome position26325284
Reported geneANO3
Mapped geneANO3
Upstream gene id
Downstream gene id
SNP gene ids63982
Upstream gene distance
Downstream gene distance
SNP risk allelers114444506-C
SNPsrs114444506
Merged0
SNP id current114444506
Contextintron_variant
Intergenic0
Allele frequency0.028
P value0.000000000002
Pvalue mlog11.698970004336
P value text
Or beta2.11
%95 Ci[1.72-2.60]
PlatformIllumina [8129524] (imputed)
CNVN
Mapped traitMMR-related febrile seizures
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006519
Study accessionGCST002674
PubMed ID25344690
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25344690
StudyCommon variants associated with general and MMR vaccine-related febrile seizures.
Disease/TraitFebrile seizures (MMR vaccine-unrelated)
Initial sample1,070 European ancestry cases, 4,118 European ancestry controls
Replication sampleUp to 1,034 European ancestry cases, Up to 1,645 European ancestry controls
Region11p14.2
Chromosome idchr11
Chromosome position26325284
Reported geneANO3
Mapped geneANO3
Upstream gene id
Downstream gene id
SNP gene ids63982
Upstream gene distance
Downstream gene distance
SNP risk allelers114444506-C
SNPsrs114444506
Merged0
SNP id current114444506
Contextintron_variant
Intergenic0
Allele frequency0.028
P value0.00000000000005
Pvalue mlog13.3010299956639
P value text
Or beta2.03
%95 Ci[1.69-2.45]
PlatformIllumina [8129384] (imputed)
CNVN
Mapped traitfebrile seizures
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0002373
Study accessionGCST002673