Human SNP ID | rs11257655 |
---|---|
Human chromosome | chr10 |
Human SNP position | 12265895 |
Pig chromosome | chr10 |
Pig SNP position | 65480897 |
PubMed ID | 22961080 |
---|---|
Journal | Diabetes |
Link | www.ncbi.nlm.nih.gov/pubmed/22961080 |
Study | A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. |
Disease/Trait | Type 2 diabetes |
Initial sample | 1,839 Han Chinese ancestry cases, 1,873 Han Chinese ancestry controls |
Replication sample | 15,979 East Asian ancestry cases, 19,360 East Asian ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 159 Filipino ancestry cases, 1,624 Filipino ancestry controls |
Region | 10p13 |
Chromosome id | chr10 |
Chromosome position | 12265895 |
Reported gene | CDC123 |
Mapped gene | CDC123 - CAMK1D |
Upstream gene id | 8872 |
Downstream gene id | 57118 |
SNP gene ids | |
Upstream gene distance | 15305 |
Downstream gene distance | 83622 |
SNP risk allele | rs11257655-T |
SNPs | rs11257655 |
Merged | 0 |
SNP id current | 11257655 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.564 |
P value | 0.000000007 |
Pvalue mlog | 8.15490195998574 |
P value text | |
Or beta | 1.15 |
%95 Ci | [1.10-1.20] |
Platform | Illumina [2234194] (imputed) |
CNV | N |
Mapped trait | type II diabetes mellitus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001360 |
Study accession | GCST001666 |
PubMed ID | 24509480 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24509480 |
Study | Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. |
Disease/Trait | Type 2 diabetes |
Initial sample | 12,171 European ancestry cases, 56,862 European ancestry controls, 6,952 East Asian ancestry cases, 11,865 East Asian ancestry controls, 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls, 1,804 Mexican ancestry cases, 779 Mexican ance |
Replication sample | 21,491 European ancestry cases, 55,647 European ancestry controls |
Region | 10p13 |
Chromosome id | chr10 |
Chromosome position | 12265895 |
Reported gene | CDC123 |
Mapped gene | CDC123 - CAMK1D |
Upstream gene id | 8872 |
Downstream gene id | 57118 |
SNP gene ids | |
Upstream gene distance | 15305 |
Downstream gene distance | 83622 |
SNP risk allele | rs11257655-T |
SNPs | rs11257655 |
Merged | 0 |
SNP id current | 11257655 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.23 |
P value | 0.000000003 |
Pvalue mlog | 8.52287874528033 |
P value text | |
Or beta | 1.06 |
%95 Ci | [1.01-1.11] |
Platform | Affymetrix, Illumina [2500000] (imputed) |
CNV | N |
Mapped trait | type II diabetes mellitus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001360 |
Study accession | GCST002352 |