SNP Detail For rs112448655
1.Mapping Information
Human SNP ID rs112448655
Human chromosome chr3
Human SNP position 140092787
Pig chromosome chr13
Pig SNP position 88798204
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region3q23
Chromosome idchr3
Chromosome position140092787
Reported geneCLSTN2
Mapped geneCLSTN2
Upstream gene id
Downstream gene id
SNP gene ids64084
Upstream gene distance
Downstream gene distance
SNP risk allelers112448655-A
SNPsrs112448655
Merged0
SNP id current112448655
Contextintron_variant
Intergenic0
Allele frequency0.997
P value0.000001
Pvalue mlog6
P value text(AA)
Or beta0.777
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region3q23
Chromosome idchr3
Chromosome position140092787
Reported geneCLSTN2
Mapped geneCLSTN2
Upstream gene id
Downstream gene id
SNP gene ids64084
Upstream gene distance
Downstream gene distance
SNP risk allelers112448655-A
SNPsrs112448655
Merged0
SNP id current112448655
Contextintron_variant
Intergenic0
Allele frequency0.997
P value0.0000003
Pvalue mlog6.52287874528033
P value text(AA)
Or beta0.163
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264