Human SNP ID | rs11191580 |
---|---|
Human chromosome | chr10 |
Human SNP position | 103146454 |
Pig chromosome | chr14 |
Pig SNP position | 124090740 |
PubMed ID | 21926974 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21926974 |
Study | Genome-wide association study identifies five new schizophrenia loci. |
Disease/Trait | Schizophrenia |
Initial sample | 9,394 European ancestry cases, 12,462 European ancestry controls |
Replication sample | 8,442 European ancestry cases, 21,397 European ancestry controls |
Region | 10q24.33 |
Chromosome id | chr10 |
Chromosome position | 103146454 |
Reported gene | NT5C2 |
Mapped gene | NT5C2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 22978 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11191580-T |
SNPs | rs11191580 |
Merged | 0 |
SNP id current | 11191580 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.91 |
P value | 0.00000003 |
Pvalue mlog | 7.52287874528033 |
P value text | |
Or beta | 1.2 |
%95 Ci | [1.13-1.26] |
Platform | Affymetrix, Illumina [1252901] (imputed) |
CNV | N |
Mapped trait | schizophrenia |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000692 |
Study accession | GCST001242 |
PubMed ID | 22688191 |
Journal | Mol Psychiatry |
Link | www.ncbi.nlm.nih.gov/pubmed/22688191 |
Study | Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. |
Disease/Trait | Schizophrenia |
Initial sample | 2,111 European ancestry cases, 2,535 European ancestry controls |
Replication sample | 11,271 European ancestry cases, 14,601 European ancestry controls |
Region | 10q24.33 |
Chromosome id | chr10 |
Chromosome position | 103146454 |
Reported gene | NT5C2, other genes, CNNM2 |
Mapped gene | NT5C2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 22978 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11191580-? |
SNPs | rs11191580 |
Merged | 0 |
SNP id current | 11191580 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.000000002 |
Pvalue mlog | 8.69897000433601 |
P value text | |
Or beta | 1.23 |
%95 Ci | [NR] |
Platform | Affymetrix [745006] |
CNV | N |
Mapped trait | schizophrenia |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000692 |
Study accession | GCST001565 |
PubMed ID | 23453885 |
Journal | Lancet |
Link | www.ncbi.nlm.nih.gov/pubmed/23453885 |
Study | Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. |
Disease/Trait | Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) |
Initial sample | 6,990 European ancestry Bipolar disorder cases, 9,227 European ancestry Major depressive disorder cases, 9,379 European ancestry Schizophrenia cases, 161 European ancestry Autism spectrum disorder cases, 4,788 European ancestry Autism spectrum disorder tr |
Replication sample | NA |
Region | 10q24.33 |
Chromosome id | chr10 |
Chromosome position | 103146454 |
Reported gene | NT5C2 |
Mapped gene | NT5C2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 22978 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11191580-? |
SNPs | rs11191580 |
Merged | 0 |
SNP id current | 11191580 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.911 |
P value | 0.00000001 |
Pvalue mlog | 8 |
P value text | (Modelling analysis) |
Or beta | |
%95 Ci | |
Platform | NR [1252901] (imputed) |
CNV | N |
Mapped trait | attention deficit hyperactivity disorder, unipolar depression, schizophrenia, autism spectrum disorder, bipolar disorder |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0003756, http://www.ebi.ac.uk/efo/EFO_0000289 |
Study accession | GCST001877 |
PubMed ID | 24861553 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24861553 |
Study | Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index. |
Disease/Trait | Body mass index |
Initial sample | 82,438 East Asian ancestry individuals, 4,301 South East Asian ancestry individuals |
Replication sample | Up to 47,352 East Asian ancestry individuals |
Region | 10q24.33 |
Chromosome id | chr10 |
Chromosome position | 103146454 |
Reported gene | NT5C2 |
Mapped gene | NT5C2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 22978 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs11191580-C |
SNPs | rs11191580 |
Merged | 0 |
SNP id current | 11191580 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.27 |
P value | 0.00000004 |
Pvalue mlog | 7.39794000867203 |
P value text | |
Or beta | 0.0295 |
%95 Ci | [0.019-0.04] unit increase |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002461 |