SNP Detail For rs11190164
1.Mapping Information
Human SNP ID rs11190164
Human chromosome chr10
Human SNP position 99591947
Pig chromosome chr14
Pig SNP position 120224674
2.Annotation Information
PubMed ID26151821
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/26151821
StudyGenome-wide association study of colorectal cancer identifies six new susceptibility loci.
Disease/TraitColorectal cancer
Initial sample18,299 European ancestry cases, 19,656 European ancestry controls
Replication sample4,725 East Asian ancestry cases, 9,969 East Asian ancestry controls
Region10q24.2
Chromosome idchr10
Chromosome position99591947
Reported geneENTPD7, COX15, CUTC, ABCC2, SLC25A28
Mapped geneNKX2-3 - SLC25A28
Upstream gene id159296
Downstream gene id81894
SNP gene ids
Upstream gene distance55423
Downstream gene distance18571
SNP risk allelers11190164-G
SNPsrs11190164
Merged0
SNP id current11190164
Contextintergenic_variant
Intergenic1
Allele frequency0.29
P value0.0000008
Pvalue mlog6.09691001300805
P value text(EA)
Or beta1.1
%95 Ci[1.05鈥?.14]
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitcolorectal cancer
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005842
Study accessionGCST003017
PubMed ID25990418
JournalSci Rep
Linkwww.ncbi.nlm.nih.gov/pubmed/25990418
StudyA new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer.
Disease/TraitColorectal cancer
Initial sample7,577 European ancestry cases, 9,979 European ancestry controls
Replication sampleNA
Region10q24.2
Chromosome idchr10
Chromosome position99591947
Reported geneSLC25A28, NKX2-3
Mapped geneNKX2-3 - SLC25A28
Upstream gene id159296
Downstream gene id81894
SNP gene ids
Upstream gene distance55423
Downstream gene distance18571
SNP risk allelers11190164-G
SNPsrs11190164
Merged0
SNP id current11190164
Contextintergenic_variant
Intergenic1
Allele frequency0.29
P value0.0000008
Pvalue mlog6.09691001300805
P value text
Or beta1.13
%95 Ci[NR]
PlatformAffymetrix, Illumina [~ 10000000] (imputed)
CNVN
Mapped traitcolorectal cancer
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005842
Study accessionGCST002919
PubMed ID26151821
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/26151821
StudyGenome-wide association study of colorectal cancer identifies six new susceptibility loci.
Disease/TraitColorectal cancer
Initial sample18,299 European ancestry cases, 19,656 European ancestry controls
Replication sample4,725 East Asian ancestry cases, 9,969 East Asian ancestry controls
Region10q24.2
Chromosome idchr10
Chromosome position99591947
Reported geneENTPD7, COX15, CUTC, ABCC2, SLC25A28
Mapped geneNKX2-3 - SLC25A28
Upstream gene id159296
Downstream gene id81894
SNP gene ids
Upstream gene distance55423
Downstream gene distance18571
SNP risk allelers11190164-G
SNPsrs11190164
Merged0
SNP id current11190164
Contextintergenic_variant
Intergenic1
Allele frequency0.29
P value0.00000004
Pvalue mlog7.39794000867203
P value text
Or beta1.09
%95 Ci[1.06-1.12]
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitcolorectal cancer
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005842
Study accessionGCST003017