SNP Detail For rs11142387
1.Mapping Information
Human SNP ID rs11142387
Human chromosome chr9
Human SNP position 70383416
Pig chromosome chr1
Pig SNP position 250057782
2.Annotation Information
PubMed ID22344221
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22344221
StudyCommon variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
Disease/TraitBody mass index
Initial sample26,620 Japanese ancestry individuals
Replication sample35,625 East Asian ancestry individuals
Region9q21.12
Chromosome idchr9
Chromosome position70383416
Reported geneKLF9
Mapped geneSMC5 - KLF9
Upstream gene id23137
Downstream gene id687
SNP gene ids
Upstream gene distance28543
Downstream gene distance1181
SNP risk allelers11142387-C
SNPsrs11142387
Merged0
SNP id current11142387
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.46
P value0.000000001
Pvalue mlog9
P value text
Or beta0.04
%95 Ci[0.018-0.062] unit increase
PlatformIllumina [2178018] (imputed)
CNVN
Mapped traitbody mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST001416
PubMed ID24861553
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24861553
StudyMeta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.
Disease/TraitBody mass index
Initial sample82,438 East Asian ancestry individuals, 4,301 South East Asian ancestry individuals
Replication sampleUp to 47,352 East Asian ancestry individuals
Region9q21.12
Chromosome idchr9
Chromosome position70383416
Reported geneKLF9
Mapped geneSMC5 - KLF9
Upstream gene id23137
Downstream gene id687
SNP gene ids
Upstream gene distance28543
Downstream gene distance1181
SNP risk allelers11142387-C
SNPsrs11142387
Merged0
SNP id current11142387
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.41
P value0.00000003
Pvalue mlog7.52287874528033
P value text
Or beta0.0324
%95 Ci[0.021-0.044] unit increase
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitbody mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002461
PubMed ID22344221
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22344221
StudyCommon variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
Disease/TraitBody mass index
Initial sample26,620 Japanese ancestry individuals
Replication sample35,625 East Asian ancestry individuals
Region2q32.2 x 9q21.12
Chromosome idchr2 x 9
Chromosome position190120954 x 70383416
Reported geneGDF8 x KLF9
Mapped geneC2orf88 x SMC5 - KLF9
Upstream gene id
Downstream gene id
SNP gene ids
Upstream gene distance
Downstream gene distance
SNP risk allelers13034723-A x rs11142387-C
SNPsrs13034723 x rs11142387
Merged0
SNP id current
Contextintron_variant x downstream_gene_variant
Intergenic
Allele frequencyNR
P value0.00000002
Pvalue mlog7.69897000433601
P value text
Or beta0.066
%95 Ci[0.042-0.090] unit increase
PlatformIllumina [2178018] (imputed)
CNVN
Mapped traitbody mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST001416