SNP Detail For rs10985070
1.Mapping Information
Human SNP ID rs10985070
Human chromosome chr9
Human SNP position 120873843
Pig chromosome chr1
Pig SNP position 293008916
2.Annotation Information
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region9q33.2
Chromosome idchr9
Chromosome position120873843
Reported geneTRAF1, C5
Mapped genePHF19
Upstream gene id
Downstream gene id
SNP gene ids26147
Upstream gene distance
Downstream gene distance
SNP risk allelers10985070-C
SNPsrs10985070
Merged0
SNP id current10985070
Contextintron_variant
Intergenic0
Allele frequency0.45
P value0.00000000005
Pvalue mlog10.3010299956639
P value text
Or beta1.08
%95 Ci[1.06-1.11]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region9q33.2
Chromosome idchr9
Chromosome position120873843
Reported geneTRAF1, C5
Mapped genePHF19
Upstream gene id
Downstream gene id
SNP gene ids26147
Upstream gene distance
Downstream gene distance
SNP risk allelers10985070-C
SNPsrs10985070
Merged0
SNP id current10985070
Contextintron_variant
Intergenic0
Allele frequency0.42
P value0.000000004
Pvalue mlog8.39794000867203
P value text(EA)
Or beta1.09
%95 Ci[1.06-1.12]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318