Human SNP ID | rs10956445 |
---|---|
Human chromosome | chr8 |
Human SNP position | 128775730 |
Pig chromosome | chr4 |
Pig SNP position | 11885851 |
PubMed ID | 24709693 |
---|---|
Journal | Pharmacogenomics J |
Link | www.ncbi.nlm.nih.gov/pubmed/24709693 |
Study | Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases. |
Disease/Trait | Response to methotrexate in juvenile idiopathic arthritis |
Initial sample | 694 European ancestry child cases |
Replication sample | NA |
Region | 8q24.21 |
Chromosome id | chr8 |
Chromosome position | 128775730 |
Reported gene | ADCY8, PVT1 |
Mapped gene | LINC00824 - LOC105375756 |
Upstream gene id | 101927774 |
Downstream gene id | 105375756 |
SNP gene ids | |
Upstream gene distance | 211051 |
Downstream gene distance | 24226 |
SNP risk allele | rs10956445-C |
SNPs | rs10956445 |
Merged | 0 |
SNP id current | 10956445 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.0000005 |
Pvalue mlog | 6.30102999566398 |
P value text | (AJC) |
Or beta | 2.73 |
%95 Ci | [1.67-3.79] unit decrease |
Platform | Illumina [586062] |
CNV | N |
Mapped trait | response to methotrexate, chronic childhood arthritis |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0031427, http://www.ebi.ac.uk/efo/EFO_0002609 |
Study accession | GCST002408 |